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NCT05448417
Exploration of Non-invasive High-frequency Oscillations in Human-machine Asynchrony in Healthy Subjects
NA trial testing Non-invasive high-frequency oscillatory ventilation in Non-invasive Ventilation in 10 participants. Status unknown.
30 December 2022
Quick facts
| Lead sponsor | Guangzhou Institute of Respiratory Disease |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | crossover |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 10 |
| Start date | 15 July 2022 |
| Primary completion | 30 December 2022 |
| Estimated completion | 1 July 2023 |
| Sites | 1 location across China |
Drugs / interventions tested
- Non-invasive high-frequency oscillatory ventilation
- Noninvasive Bilevel Positive Pressure Ventilation
Conditions studied
- Non-invasive Ventilation — all drugs for Non-invasive Ventilation →
- Healthy Subjects — all drugs for Healthy Subjects →
Sponsor
Guangzhou Institute of Respiratory Disease
Who can join
Adults 25 to 40, any sex, with Non-invasive Ventilation or Healthy Subjects. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
High-frequency oscillatory ventilation (HFOV), as an ideal lung-protecting ventilation method, has been gradually applied to neonatal intensive care treatment, and is currently recommended as a rescue method for neonatal acute respiratory distress syndrome (ARDS) after conventional mechanical treatment fails. ventilation. Non-invasive high-frequency oscillatory ventilation (nHFOV) combines the advantages of HFOV and non-invasive ventilation methods, and has become a research hotspot in this field. Recommended to avoid intubation after failure of conventional non-invasive ventilation therapy. There is a lack of large-scale clinical trials systematically exploring its efficacy for intubation therapy. The increasing clinical application of nHFOV has also enriched its application in the treatment of other diseases. Human-machine asynchrony during non-invasive ventilation will seriously affect its efficacy, but no one has reported on the research related to nHFOV human-machine asynchrony.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT05448417
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Related trials
Other trials of Non-invasive high-frequency oscillatory ventilation
Trials testing the same drug.
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- NCT05435183 — Effect of Noninvasive High Frequency Oscillatory Ventilation on Improving Carbon Dioxide Clearance in AECOPD Patients · NA · unknown
Other recruiting trials for Non-invasive Ventilation
Currently open trials in the same condition.
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- NCT06072339 — Optimization of Positive End Expiratory Pressure by Use of Pulmonary Ultrasound for Patients With Blunt Chest Trauma Tre · NA · recruiting
Other Guangzhou Institute of Respiratory Disease trials
Trials by the same sponsor.
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- NCT06909383 — Nanocrystalline Megestrol Acetate for the Treatment of Anorexia-Cachexia Syndrome in Extensive-Stage Small Cell Lung Can · Phase 2 · not yet recruiting
- NCT07005999 — Interventional Ablation for Early-stage Lung Cancer · active not recruiting
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05448417 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Guangzhou Institute of Respiratory Disease
- Last refreshed: 7 July 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05448417.
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