Last reviewed · How we verify
NCT05448274
The Effects of a Ruminococcus Torques Strain Bacterium in Healthy Adults.
NA trial testing Placebo in Overweight in 32 participants. Completed in 14 September 2023.
6 September 2023
Quick facts
| Lead sponsor | Oluf Pedersen |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | crossover |
| Masking | quadruple |
| Primary purpose | other |
| Enrollment | 32 |
| Start date | 3 May 2023 |
| Primary completion | 6 September 2023 |
| Estimated completion | 14 September 2023 |
| Sites | 1 location across Denmark |
Drugs / interventions tested
- Placebo
- Ruminococcus torques — full drug profile →
Conditions studied
- Overweight — all drugs for Overweight →
- Healthy — all drugs for Healthy →
Sponsor
Oluf Pedersen — full company profile →
Who can join
Adults 18 to 40, any sex, with Overweight or Healthy. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
A randomized, placebo controlled crossover study investigating the potential metabolic effects of the naturally occurring gut microbe Ruminococcus torques in healthy, overweight adults.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
<i>Lachnospiraceae</i> are emerging industrial biocatalysts and biotherapeutics.
Zaplana T, Miele S, Tolonen AC. · · 2023 · cited 57× · PMID 38239921 · DOI 10.3389/fbioe.2023.1324396 -
The Role of Beneficial Microbiota in COVID-19: Insights from Key Bacterial Genera.
Rampelotto PH, Taufer CR, da Silva J. · · 2025 · PMID 40431202 · DOI 10.3390/microorganisms13051029
Verify or expand the search:
- PubMed search for NCT05448274
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05448274 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Oluf Pedersen
- Last refreshed: 21 September 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05448274.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing