NCT05448040 is a NA clinical trial of Socket preservation in Socket Sealing, sponsored by Universidade Salgado de Oliveira.

Who is sponsoring NCT05448040?

NCT05448040 is sponsored by Universidade Salgado de Oliveira.

What drugs are being tested in NCT05448040?

Interventions in NCT05448040: Socket preservation.

What condition does NCT05448040 study?

NCT05448040 studies Socket Sealing, Free Gingival Graft, Collagen Membrane.

Is NCT05448040 still recruiting?

NCT05448040 is currently completed. Last updated 7 July 2022.

Last reviewed 2022-07-07 · How we verify

NCT05448040

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Clinical and Histological Assessment of Free Gingival Graft or Collagen Matrix for Socket Sealing After Bone Grafting

Completed NA Last updated 7 July 2022

What this trial tests

NA trial testing Socket preservation in Socket Sealing in 18 participants. Completed in 30 November 2021.

Timeline

1 February 2018

Primary endpoint
18 September 2020

30 November 2021

Quick facts

Lead sponsor	Universidade Salgado de Oliveira
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	triple
Primary purpose	treatment
Enrollment	18
Start date	1 February 2018
Primary completion	18 September 2020
Estimated completion	30 November 2021
Sites	1 location across United States

Drugs / interventions tested

Socket preservation

Conditions studied

Socket Sealing — all drugs for Socket Sealing →
Free Gingival Graft — all drugs for Free Gingival Graft →
Collagen Membrane — all drugs for Collagen Membrane →

Sponsor

Universidade Salgado de Oliveira

Who can join

Adults 18 to 55, any sex, with Socket Sealing or Free Gingival Graft. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The goal of this study was to compare, clinical and histologically, the use of the suine collagen matrix (Mucograft Seal \[MS\], Geisthlich®) and the free gingival graft (FGG) for the alveolar sealing after inserted bone graft biomaterial. It was included 18 patients with tooth referred to extraction (maxilar incisives, canines, or pre-molars) which were randomly divided in 2 groups, according to the material for alveolus sealing: control (FGG) and test (MS). After the minimally traumatic extraction, all the alveoli were filled with bovine mineral matrix (Bio-Oss®), and the material for alveolar sealing were positioned and stabilized with sutures. The follow-up (clinical and photographic) happened on the immediate post-operatory period, and with 3, 7, 15, 30, 60, 90, and 120 days. After 120 days, before implant placement, tissues samples were obtained with a 3.5mm punch scalpel for histological analysis. Qualitative information related to the patient's perception considering the treatment were collected.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

Other trials of Socket preservation

Trials testing the same drug.

NCT07023757 — Effect of Age on PRF Quality; Assessed by Evaluating Healing Outcomes of ARP · NA · enrolling by invitation
NCT07020650 — The Effectiveness of Carbonate Apatite Bone Graft for Alveolar Ridge Preservation · NA · enrolling by invitation
NCT05592158 — Evaluation of the Effectiveness of an Amnion-chorion Membrane for Alveolar Ridge Preservation · NA · completed
NCT05889377 — Socket Preservation Technique Using Bovine Bone, Platelet Rich Fibrin Or A Combination Of Both: A Clinical, Radiographic · NA · completed
NCT04356001 — The "One-piece" Autologous Tuberosity Graft · NA · completed

Other Universidade Salgado de Oliveira trials

Trials by the same sponsor.

NCT06591156 — Gingival Recessions Treated by CAF with or Without PRF · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05448040 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Universidade Salgado de Oliveira
Last refreshed: 7 July 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05448040.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing