Last reviewed · How we verify

NCT05439252: ESSIST

Exercise Snacking to Improve Strength and STability: ESISST Pilot Study

Completed NA Results posted Last updated 4 October 2024
What this trial tests

NA trial testing Exercise Snacking in Acceptability of an Exercise Intervention in 21 participants. Completed in 20 January 2023.

Timeline
1 August 2022
Primary endpoint
20 January 2023
20 January 2023

Quick facts

Lead sponsorUniversity of Bath
PhaseNA
StatusCompleted
Study typeINTERVENTIONAL
Allocationna
Designsingle group
Maskingnone
Primary purposeother
Enrollment21
Start date1 August 2022
Primary completion20 January 2023
Estimated completion20 January 2023
Sites1 location across United Kingdom

Drugs / interventions tested

Conditions studied

Sponsor

University of Bath

Who can join

65 and older, any sex, with Acceptability of an Exercise Intervention. Patients with the condition only — healthy volunteers not accepted.

Results — posted to ClinicalTrials.gov

Per-arm endpoint measurements with 95% confidence intervals where reported. Source: trial results section.

Acceptability of the Intervention Primary · 28-days (post intervention)

Participants will be asked to complete a Theoretical Framework of Acceptability questionnaire on their experiences of the exercise snacking questionnaire. The scale scores range from 0 to 5 with high scores indicating greater acceptability, and the total score representing the mean average of 7 individual domains of acceptability (each also rated 0-5).

GroupValue95% CI
Exercise Snacking Group4.6± 0.6
Attitudes to Exercise Secondary · 28-days (pre-to-post intervention)

Outcome Expectancy for Exercise Questionnaire Score on a scale of 0-5, with higher scores indicating higher outcome expectancy

Baseline
GroupValue95% CI
Exercise Snacking Group4.0± 0.6
Post-intervention
GroupValue95% CI
Exercise Snacking Group4.3± 0.5
Self-confidence for Exercise Secondary · 28-days (pre-to-post intervention)

The 'Barriers Self-Efficacy Scale', (BARSE), to assess participants perceived capabilities to exercise. The scale ranges from 0-100, with a higher score indicating higher self-efficacy.

Baseline
GroupValue95% CI
Exercise Snacking Group70.1± 26.2
Post-intervention
GroupValue95% CI
Exercise Snacking Group66.3± 16.3
Psychological Need Satisfaction for Exercise Secondary · 28-days (pre-to-post intervention)

Psychological need satisfaction for exercise questionnaire Score on a scale of 0-6, with higher scores indicating a greater satisfaction of basic psychological needs

Baseline
GroupValue95% CI
Exercise Snacking Group5± 0.7
Post-intervention
GroupValue95% CI
Exercise Snacking Group5± .7
Current Mental Health Secondary · 28-days (pre-to-post intervention)

Patient Health Questionnaire Score on a scale of 0-27, with lower scores indicating less depression

Baseline
GroupValue95% CI
Exercise Snacking Group3.5± 3.5
Post-intervention
GroupValue95% CI
Exercise Snacking Group3.7± 3.7
Patient Anxiety Secondary · 28-days (pre-to-post intervention)

Generalised Anxiety Disorder Assessment Score on a scale of 0-21, with lower scores indicating lower anxiety

Baseline
GroupValue95% CI
Exercise Snacking Group2± 2
Poat-intervention
GroupValue95% CI
Exercise Snacking Group1.6± 2.1
General Health Secondary · 28-days (pre-to-post intervention)

Short Form Health Survey (SF-36) Separate scales from 0 to 100 for each of the two domains (physical and mental), with higher scores meaning better health status in both. The two domains are reported separately but not combined.

Physical Domain: Baseline
GroupValue95% CI
Exercise Snacking Group48.5± 8.0
Physical Domain: Post-Intervention
GroupValue95% CI
Exercise Snacking Group46.1± 6.8
Mental Domain: Baseline
GroupValue95% CI
Exercise Snacking Group47.5± 11.9
Mental Domain: Post-intervention
GroupValue95% CI
Exercise Snacking Group51.3± 12.8
Patient Vitality Secondary · 28-days (pre-to-post intervention)

Subjective Vitality Index Score on a scale of 0-49, with higher scores indicating greater vitality

Baseline
GroupValue95% CI
Exercise Snacking Group30.8± 8.7
Post-intervention
GroupValue95% CI
Exercise Snacking Group32.4± 6.1
Patient Life Satisfaction Secondary · 28-days (pre-to-post intervention)

Life Satisfaction Scale Score on a scale of 0-35, with higher scores indicating greater satisfaction with life

Baseline
GroupValue95% CI
Exercise Snacking Group29± 4.1
Post-intervention
GroupValue95% CI
Exercise Snacking Group27.7± 5.5
Patient Quality of Life Secondary · 28-days (pre-to-post intervention)

Overall quality of life scale Score on a scale of 0-100, with higher scores indicating better quality of life

Baseline
GroupValue95% CI
Exercise Snacking Group82.5± 11.1
Post-intervention
GroupValue95% CI
Exercise Snacking Group79.4± 8.2
Cognitive Assessment Secondary · 28-days (pre-to-post intervention)

Montreal Cognitive Assessment Score on a scale of 0-30, with lower scores indicating greater cognitive impairment

Baseline
GroupValue95% CI
Exercise Snacking Group23.3± 4.0
Post-intervention
GroupValue95% CI
Exercise Snacking Group24.3± 4.0
Cognitive Assessment Secondary · 28-days (pre-to-post intervention)

Groningen Frailty Index Score on a scale of 0-15, with higher scores being more frail

Baseline
GroupValue95% CI
Exercise Snacking Group3.9± 2.1
Post-intervention
GroupValue95% CI
Exercise Snacking Group3.6± 1.9

Sponsor's own description

As we age, muscles can become progressively weaker to the point that tasks of daily living cannot be carried out safely. However, regular resistance exercise training has been shown to maintain and even increase muscle strength in older adults. Previous research has identified a homebased, non-loaded, lower limb only, 'exercise snacking' model that does not require exercise equipment or supervision as a viable alternative exercise strategy to traditional resistance exercise, with potential to improve leg muscle strength in healthy older adults. This approach has been shown to be feasible and acceptable to general healthy older adult population, however this approach to exercise focussed on improving strength has not been considered in a clinical population. This research seeks to investigate the acceptability of 28 days of homebased exercise snacking in outpatients with attending the memory clinic at the Research Institute for Care of the Elderly (RICE) Centre in Bath, UK, with diagnosis limited to mild cognitive impairment only. This study will improve understanding of how zero-cost exercise strategies to potentially improve muscle function and delay frailty could be incorporated in daily routines of older adults.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

  1. Exercise snacking to improve physical function in pre-frail older adult memory clinic patients: a 28-day pilot study.
    Western MJ, Welsh T, Keen K, Bishop V, et al · · 2023 · cited 17× · PMID 37542234 · DOI 10.1186/s12877-023-04169-6
  2. Exercise snacking to improve physical function in pre-frail older adult memory clinic patients: a 28-day pilot study
    Western MJ, Welsh T, Keen K, Bishop V, et al · · 2023 · DOI 10.21203/rs.3.rs-2662239/v1

Verify or expand the search:

Other University of Bath trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05439252.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing