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NCT05436379: TREND
Treatment, Emotion, and Neuromodulation of Depression (TREND) Study
NA trial testing Theta Burst Stimulation in Depression in 21 participants. Completed in 30 November 2025.
30 November 2025
Quick facts
| Lead sponsor | Erika Forbes |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 21 |
| Start date | 17 June 2022 |
| Primary completion | 30 November 2025 |
| Estimated completion | 30 November 2025 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Theta Burst Stimulation
Conditions studied
- Depression — all drugs for Depression →
Sponsor
Erika Forbes
Who can join
Adults 18 to 26, any sex, with Depression. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The investigators will administer theta burst stimulation (TBS) in efforts to observe a decrease in severity of reported depression symptoms. A subset of participants will receive positive affect training during this intervention.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT05436379
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Theta Burst Stimulation
Trials testing the same drug.
- NCT07399431 — Theta Burst Stimulation in the Management of Methamphetamine Use Disorder in Indonesia · NA · completed
- NCT06528938 — Comparing the Efficacy of Accelerated vs. Standard fMRI-guided iTBS in Treating Adolescents Depression · NA · recruiting
- NCT06658769 — Use of Transcranial Magnetic Stimulation in the Post-Operative Cognitive Dysfunction in Elderly · NA · recruiting
- NCT05388539 — TBS Treatment for Treatment-Resistant Depression · NA · completed
- NCT05049460 — Adjunctive Transcranial Stimulation to Reduce Impulsivity in Opiate Use Disorder · NA · completed
Other recruiting trials for Depression
Currently open trials in the same condition.
- NCT07336238 — Group Retreat Psilocybin Therapy for the Treatment of Anxiety and Depression in Patients With Metastatic Solid Tumors or · Phase 2 · recruiting
- NCT06906939 — A Randomized Pilot rTMS Trial for Knee Arthritis Pain and Depression · EARLY_PHASE1 · recruiting
- NCT07517549 — Sexual Health Education During Pregnancy · NA · recruiting
- NCT06408246 — ACE-D Aim 3 Clinical Cognitive Trial to Enhance Translation in Depression · Phase 2 · recruiting
- NCT07449676 — Effects of an Innovative TCM-based Tui Jing Therapy on Psychological and Neurophysiological Functions in Depression · NA · recruiting
Other Erika Forbes trials
Trials by the same sponsor.
- NCT05487885 — Anhedonia, Development, and Emotions: Phenotyping and Therapeutics · Phase 4 · completed
- NCT03737032 — Theta Burst Stimulation in Young Adults With Depression · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05436379 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Erika Forbes
- Last refreshed: 30 December 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05436379.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing