Who is sponsoring NCT05434377?

NCT05434377 is sponsored by Chulalongkorn University.

What drugs are being tested in NCT05434377?

Interventions in NCT05434377: ergocalciferol supplementation, dialysis techniques, sunlight exposure time.

What condition does NCT05434377 study?

NCT05434377 studies Vitamin D Deficiency, End Stage Renal Disease.

Is NCT05434377 still recruiting?

NCT05434377 is currently completed. Last updated 8 February 2024.

Last reviewed 2024-02-08 · How we verify

NCT05434377

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

A Study of Fixed Dose Versus Serum Level-Based Titration Regimen of Vitamin D Supplementation in Dialysis Patients

Completed NA Last updated 8 February 2024

What this trial tests

NA trial testing ergocalciferol supplementation in Vitamin D Deficiency in 78 participants. Completed in 31 December 2023.

Timeline

1 August 2022

Primary endpoint
31 May 2023

31 December 2023

Quick facts

Lead sponsor	Chulalongkorn University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	treatment
Enrollment	78
Start date	1 August 2022
Primary completion	31 May 2023
Estimated completion	31 December 2023
Sites	1 location across Thailand

Drugs / interventions tested

ergocalciferol supplementation — full drug profile →
dialysis techniques
sunlight exposure time

Conditions studied

Vitamin D Deficiency — all drugs for Vitamin D Deficiency →
End Stage Renal Disease — all drugs for End Stage Renal Disease →

Sponsor

Chulalongkorn University

Who can join

Adults 18 to 100, any sex, with Vitamin D Deficiency or End Stage Renal Disease. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Vitamin D insufficiency, defined as serum 25-hydroxyvitamin (OH) D level less than 30 ng/ml, is highly prevalent not only in the general population but also in chronic kidney disease (CKD) population. Many guidelines including the National Kidney Foundation-Kidney Disease Outcomes Quality Initiative (NKF-KDOQI) have consistently recommended vitamin D supplementation in patients with pre-dialysis CKD with vitamin D insufficiency with ergocalciferol or cholecalciferol to achieve 25(OH)D level of more than 30 ng/ml using serum levels-based titration regimen. However, this protocol has not been studied in end stage kidney disease patients treated with maintenance dialysis.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Sarcopenia in chronic kidney disease: from bench to bedside.
Kim DW, Song SH. · · 2023 · cited 18× · PMID 37077132 · DOI 10.3904/kjim.2022.338
Clinical features and molecular mechanism of muscle wasting in end stage renal disease.
Ju SH, Yi HS. · · 2023 · cited 5× · PMID 37482754

Verify or expand the search:

Other recruiting trials for Vitamin D Deficiency

Currently open trials in the same condition.

NCT07317830 — Effects of Different Vitamin D3 Formulations in Vitamin D-Deficient Adults · NA · recruiting
NCT07366970 — Is There a Benefit From Addition of Exercise in Diabetic Patients With ED Who Complain Low Vitamin D? · NA · recruiting
NCT07481240 — A Household-Based Dietary Intervention Study of Vitamin D Fortified Bread in Irish Families · NA · recruiting
NCT07006714 — Preoperative Correction of Vitamin D Deficiency in Total Joint Arthroplasty (TJA) · Phase 4 · active not recruiting
NCT07200011 — Effect of Vitamin D on the Clinical and Radiographic of Unsplinted Mandibular Implant Overdentures · active not recruiting

Other Chulalongkorn University trials

Trials by the same sponsor.

NCT07458659 — Clinical Study of BCMA-Targeted CAR T-Cell Injection in the Treatment of Patients With Relapsed/Refractory Multiple Myel · EARLY_PHASE1 · not yet recruiting
NCT07346118 — Fluid Balance Guided by Modified Venous Excess Ultrasonography Versus Standard Care in Patients With Acute Kidney Injury · NA · not yet recruiting
NCT07388862 — Comparison of Treatment Outcome of Pulpotomy With Versus Without Dental Operating Microscope in Carious Mature Permanent · EARLY_PHASE1 · not yet recruiting
NCT07373977 — Comparison of Postoperative Pain After Pulpotomy Performed With Versus Without Dental Operating Microscope in Carious Ma · EARLY_PHASE1 · not yet recruiting
NCT07078929 — Clinical Trial of CMD63 Chimeric Antigen Receptor T-cell (CAR T-cell) in Children With Acute Lymphoblastic Leukemia (ALL · Phase 1 · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05434377 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Chulalongkorn University
Last refreshed: 8 February 2024

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05434377.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing