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NCT05433090: Inpatient SICP

An Inpatient Advance Care Planning Intervention for Older Patients With Hematologic Malignancies

Completed NA Results posted Last updated 31 March 2026
What this trial tests

NA trial testing Inpatient serious illness care program in Hematologic Malignancies in 41 participants. Completed in 14 November 2024.

Timeline
23 November 2022
Primary endpoint
23 August 2024
14 November 2024

Quick facts

Lead sponsorUniversity of Rochester
PhaseNA
StatusCompleted
Study typeINTERVENTIONAL
Allocationna
Designsingle group
Maskingnone
Primary purposehealth services research
Enrollment41
Start date23 November 2022
Primary completion23 August 2024
Estimated completion14 November 2024
Sites1 location across United States

Drugs / interventions tested

Conditions studied

Sponsor

University of Rochester

Who can join

60 and older, any sex, with Hematologic Malignancies. Patients with the condition only — healthy volunteers not accepted.

Results — posted to ClinicalTrials.gov

Per-arm endpoint measurements with 95% confidence intervals where reported. Source: trial results section.

Retention Rate Primary · From consent until completion of the ACP intervention visit, usually within 1 week.

Retention rate is the percentage of consented patients who completed the ACP intervention visit. A retention rate of \>70% was considered feasible.

Retained - completed ACP intervention
GroupValue95% CI
Advanced Care Planning38
Not retained - didn't complete ACP intervention
GroupValue95% CI
Advanced Care Planning3
Advance Directive Completion - HCP Secondary · From baseline (pre-intervention) to 1 year post-intervention. The time interval is approximately 1 year.

Data on the patient's completion of scanned healthcare proxy form that was completed with their physician was collected via the electronic medical record. This is expressed as a percentage.

Baseline
GroupValue95% CI
Advanced Care Planning23
Advanced Care Planning18
After ACP Intervention
GroupValue95% CI
Advanced Care Planning31
Advanced Care Planning10
Advance Directive Completion - MOLST Secondary · From baseline (pre-intervention) to 1 year post-intervention. The time interval is approximately 1 year.

Data on the patient's completion of scanned medical order for life sustaining treatment (MOLST) form that was completed with their clinician was collected via the electronic medical record. This is expressed as a percentage.

Baseline
GroupValue95% CI
Advanced Care Planning7
Advanced Care Planning34
After ACP Intervention
GroupValue95% CI
Advanced Care Planning20
Advanced Care Planning21

Sponsor's own description

This is a pilot study to assess the preliminary efficacy of an inpatient advance care planning intervention on outcomes in older patients with hematologic malignancies

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

  1. An inpatient Serious Illness Care Program for older patients with hematologic malignancies: A single-arm pilot study.
    Locastro M, Wang Y, Baran AM, Mortaz Hedjri S, et al · · 2026 · PMID 41949389 · DOI 10.1182/bloodadvances.2025018200
  2. Challenges in hospice and end-of-life care in the transfusion-dependent patient.
    Rodenbach R, Caprio T, Loh KP. · · 2024 · PMID 39644067 · DOI 10.1182/hematology.2024000560

Verify or expand the search:

Other recruiting trials for Hematologic Malignancies

Currently open trials in the same condition.

Other University of Rochester trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05433090.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing