Who is sponsoring NCT05432271?

NCT05432271 is sponsored by University of Pennsylvania.

What drugs are being tested in NCT05432271?

Interventions in NCT05432271: Exposure to calorie information, Exposure to healthy labels only, Exposure to healthiness information, Exposure to physical activity equivalents, Exposure to "high in" nutrient warning labels.

What condition does NCT05432271 study?

NCT05432271 studies Food Preferences, Obesity, Weight Gain.

Is NCT05432271 still recruiting?

NCT05432271 is currently completed. Last updated 20 December 2023.

Are results published for NCT05432271?

Yes — primary outcome results have been posted to ClinicalTrials.gov. See the outcomes section above for details.

Last reviewed 2023-12-20 · How we verify

NCT05432271: VLO

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Online Food and Beverage Labels and Vending Machine Selections

Completed NA Results posted Last updated 20 December 2023

What this trial tests

NA trial testing Exposure to calorie information in Food Preferences in 8,145 participants. Completed in 3 December 2022.

Timeline

16 November 2022

Primary endpoint
3 December 2022

3 December 2022

Quick facts

Lead sponsor	University of Pennsylvania
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	prevention
Enrollment	8,145
Start date	16 November 2022
Primary completion	3 December 2022
Estimated completion	3 December 2022
Sites	1 location across United States

Drugs / interventions tested

Exposure to calorie information
Exposure to healthy labels only
Exposure to healthiness information
Exposure to physical activity equivalents
Exposure to "high in" nutrient warning labels

Conditions studied

Food Preferences — all drugs for Food Preferences →
Obesity — all drugs for Obesity →
Weight Gain — all drugs for Weight Gain →

Sponsor

University of Pennsylvania

Who can join

18 and older, any sex, with Food Preferences or Obesity. Patients with the condition only — healthy volunteers not accepted.

Results — posted to ClinicalTrials.gov

Per-arm endpoint measurements with 95% confidence intervals where reported. Source: trial results section.

Number of Participants Purchasing Beverages With Calories Primary · The survey will take up to 20 minutes.

Participants will select a beverage to purchase from the online vending machine. Outcome is binary: purchased a beverage with calories or not.

Group	Value	95% CI
Control	1005
Green Labels	765
Traffic Light Labels	763
Physical Activity Calorie Equivalent Labels	748
"High in" Nutrient Warning Labels	847

Calories Purchased From Beverages, if Beverage With Calories Chosen Primary · The survey will take up to 20 minutes.

Participants will select a beverage to purchase from the online vending machine. Outcome is calories in beverage chosen to purchase - only for those participants who chose a beverage with calories.

Group	Value	95% CI
Control	199	± 84
Green Labels	190	± 90
Traffic Light Labels	196	± 87
Physical Activity Calorie Equivalent Labels	184	± 92
"High in" Nutrient Warning Labels	183	± 93

Calories Purchased From Snacks Primary · The survey will take up to 20 minutes.

Participants will select a snack to purchase from the online vending machine. Outcome is calories in snacks chosen to purchase.

Group	Value	95% CI
Control	183	± 69
Green Labels	170	± 62
Traffic Light Labels	169	± 63
Physical Activity Calorie Equivalent Labels	164	± 68
"High in" Nutrient Warning Labels	169	± 67

Likelihood of Selecting a Healthy Beverage Secondary · The survey will take up to 20 minutes.

Participants will select a beverage to purchase in the virtual store. Outcome is percentage of people selecting a healthy beverage (green labeled in the traffic light condition)

Group	Value	95% CI
Control	311
Green Labels	526
Traffic Light Labels	601
Physical Activity Calorie Equivalent Labels	473
"High in" Nutrient Warning Labels	412

Likelihood of Selecting a Moderately Healthy Beverage Secondary · The survey will take up to 20 minutes.

Participants will select a beverage to purchase in the virtual store. Outcome is percentage of people selecting a moderately healthy beverage (yellow labeled in the traffic light condition)

Group	Value	95% CI
Control	459
Green Labels	471
Traffic Light Labels	420
Physical Activity Calorie Equivalent Labels	564
"High in" Nutrient Warning Labels	549

Likelihood of Selecting a Less Healthy Beverage Secondary · The survey will take up to 20 minutes.

Participants will select a beverage to purchase in the virtual store. Outcome is percentage of people selecting a less healthy beverage (red labeled in the traffic light condition)

Group	Value	95% CI
Control	822
Green Labels	590
Traffic Light Labels	567
Physical Activity Calorie Equivalent Labels	552
"High in" Nutrient Warning Labels	626

Likelihood of Selecting a Healthy Snack Secondary · The survey will take up to 20 minutes.

Participants will select a snack to purchase in the virtual store. Outcome is percentage of people selecting a healthy snack (green labeled in the traffic light condition)

Group	Value	95% CI
Control	268
Green Labels	480
Traffic Light Labels	494
Physical Activity Calorie Equivalent Labels	384
"High in" Nutrient Warning Labels	427

Likelihood of Selecting a Moderately Healthy Snack Secondary · The survey will take up to 20 minutes.

Participants will select a snack to purchase in the virtual store. Outcome is percentage of people selecting a moderately healthy snack (yellow labeled in the traffic light condition)

Group	Value	95% CI
Control	677
Green Labels	619
Traffic Light Labels	673
Physical Activity Calorie Equivalent Labels	733
"High in" Nutrient Warning Labels	706

Likelihood of Selecting a Less Healthy Snack Secondary · The survey will take up to 20 minutes.

Participants will select a snack to purchase in the virtual store. Outcome is percentage of people selecting a less healthy snack (red labeled in the traffic light condition)

Group	Value	95% CI
Control	648
Green Labels	488
Traffic Light Labels	421
Physical Activity Calorie Equivalent Labels	473
"High in" Nutrient Warning Labels	454

Saturated Fat Purchased From Beverages Secondary · The survey will take up to 20 minutes.

Participants will select a beverage to purchase from the online vending machine. Outcome is saturated fat in beverage chosen to purchase.

Group	Value	95% CI
Control	0	0 – 0
Green Labels	0	0 – 0
Traffic Light Labels	0	0 – 0
Physical Activity Calorie Equivalent Labels	0	0 – 0
"High in" Nutrient Warning Labels	0	0 – 0

Sodium Purchased From Beverages Secondary · The survey will take up to 20 minutes.

Participants will select a beverage to purchase from the online vending machine. Outcome is sodium in beverage chosen to purchase.

Group	Value	95% CI
Control	94	± 82
Green Labels	81	± 85
Traffic Light Labels	71	± 82
Physical Activity Calorie Equivalent Labels	88	± 88
"High in" Nutrient Warning Labels	93	± 88

Total Sugar Purchased From Beverages Secondary · The survey will take up to 20 minutes.

Participants will select a beverage to purchase from the online vending machine. Outcome is total sugar in beverage chosen to purchase.

Group	Value	95% CI
Control	33	± 31
Green Labels	24	± 30
Traffic Light Labels	24	± 30
Physical Activity Calorie Equivalent Labels	22	± 30
"High in" Nutrient Warning Labels	25	± 30

Sponsor's own description

The aim of this study is to compare the impact of 5 different types of front of package (FOP) food and beverage labels: 1) calorie labels \[control\], 2) green labels on healthy foods, 3) red/yellow/green labels on less healthy/moderately healthy/healthy foods, 4) physical activity calorie equivalent labels, and 5) "High in" nutrient warning labels) on consumers' beverage and snack selections.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Effects of 4 Interpretive Front-of-Package Labeling Systems on Hypothetical Beverage and Snack Selections: A Randomized Clinical Trial.
Grummon AH, Gibson LA, Musicus AA, Stephens-Shields AJ, et al · · 2023 · cited 14× · PMID 37703015 · DOI 10.1001/jamanetworkopen.2023.33515

Verify or expand the search:

Other trials of Exposure to calorie information

Trials testing the same drug.

NCT05592340 — Restaurant Menu Carbon Footprint Labeling · NA · completed
NCT05079477 — Online Study of the Effects of Sugary Drink Warning Labels on Consumption · NA · completed

Other recruiting trials for Food Preferences

Currently open trials in the same condition.

NCT07042412 — Ta'am Mustadam Intervention to Promote Sustainable Food Choices · NA · active not recruiting
NCT06432517 — Sources and Mechanisms of Energy Compensation · NA · recruiting
NCT06175988 — Visceral Adiposity, Vagal Tone and Food Preferences: a Pilot Study · recruiting
NCT06090409 — Encouraging a Plant Based Diet in an Underserved Urban Population · NA · recruiting

Other University of Pennsylvania trials

Trials by the same sponsor.

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NCT07415772 — Effect of cTBS on Startle and TMS-evoked BOLD · NA · not yet recruiting
NCT07489430 — DaxibotulinumtoxinA for Blepharospasm · Phase 2 · not yet recruiting
NCT07463131 — Negative Income Tax Trial · NA · not yet recruiting
NCT06645769 — Na-Phenylbutyrate VAscular Trial · EARLY_PHASE1 · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05432271 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of Pennsylvania
Last refreshed: 20 December 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05432271.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing