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NCT05431686

Group Visits for High Risk Type 1 Diabetes (T1D)

Completed NA Results posted Last updated 22 December 2025
What this trial tests

NA trial testing SMA visits in Type 1 Diabetes in 14 participants. Completed in 1 July 2025.

Timeline
16 February 2022
Primary endpoint
1 July 2025
1 July 2025

Quick facts

Lead sponsorChildren's National Research Institute
PhaseNA
StatusCompleted
Study typeINTERVENTIONAL
Allocationna
Designsingle group
Maskingnone
Primary purposesupportive care
Enrollment14
Start date16 February 2022
Primary completion1 July 2025
Estimated completion1 July 2025
Sites1 location across United States

Drugs / interventions tested

Conditions studied

Sponsor

Children's National Research Institute

Who can join

8 and older, any sex, with Type 1 Diabetes. Patients with the condition only — healthy volunteers not accepted.

Results — posted to ClinicalTrials.gov

Per-arm endpoint measurements with 95% confidence intervals where reported. Source: trial results section.

Percentage of Eligible Participants Who Agreed to Participate as Assessed by Tracking Those Who Were Approached to Participate and Those Who Agreed to Participate Primary · 12 months

Investigators will track all patients who screened eligible to participate in the study, as well as those who that were contacted to gauge interest in participating. Investigators will track the percent of people who agreed to participate from those that were approached, with the goal of \>60% of those reached/eligible to participate agreeing to enroll as a measure of feasibility.

GroupValue95% CI
SMA Visit Intervention Arm14
Percentage of Participants With CGM Use, as Assessed by Tracking CGM Use Status From Enrollment to the End of the Study. Primary · 18 months

For those who agree to enroll, investigators will classify participant's CGM use status at time of enrollment as either current CGM users, never CGM users, or those with CGM attrition. At the completion of the study, CGM use status will be assessed, with the goal of \>80% current CGM users among study participants as a measure of feasibility.

GroupValue95% CI
SMA Visit Intervention Arm87.580.1 – 92.7
Frequency of SMA Sessions Attended, as Assessed by Tracking Study Visit Attendance. Primary · 12 months

For those who agree to enroll, investigators will document if participants attended or were absent from scheduled study visits. At the completion of the study, attendance will be assessed, with the goal of \>80% sessions attended among study participants as a measure of feasibility.

GroupValue95% CI
SMA Visit Intervention Arm9080 – 100
Perceived Satisfaction of SMA Intervention as Assessed by Semi-structured Interviews. Primary · 12 months

Thematic analysis of qualitative data will be conducted by two team members who independently review interview transcripts to generate initial codes. Initial codes will be discussed by the group to generate a list of second-cycle codes and each team member will then apply coding framework to all transcripts before identifying dominant themes. ATLAS.ti software will be used to organize and analyze qualitative data.

GroupValue95% CI
SMA Visit Intervention Arm2
Percentage of Time in Range (70-180 mg/dl) Secondary · baseline, 3 months, 6 months, 9 months, 12 months, 15 months, 18 months

We will look at differences in the percent of time that blood sugar values are in range within subject measures across the SMA intervention and during the follow up period.

Baseline
GroupValue95% CI
SMA Visit Intervention Arm27.25± 1.71
3 months
GroupValue95% CI
SMA Visit Intervention Arm21.75± 10.56
6 months
GroupValue95% CI
SMA Visit Intervention Arm23.67± 3.79
9 months
GroupValue95% CI
SMA Visit Intervention Arm29.00± 5.66
12 months
GroupValue95% CI
SMA Visit Intervention Arm33.33± 8.33
15 months
GroupValue95% CI
SMA Visit Intervention Arm38.00± 3.61
18 months
GroupValue95% CI
SMA Visit Intervention Arm27.00± 9.17
Continuous Glucose Monitor Time Below Range (<70 mg/dL) Secondary · baseline, 3 months, 6 months, 9 months, 12 months, 15 months, 18 months

We will look at differences in the percent of time that blood sugar values are below range within subject measures across the SMA intervention and during the follow up period.

Baseline
GroupValue95% CI
SMA Visit Intervention Arm2.45± 1.73
3 months
GroupValue95% CI
SMA Visit Intervention Arm0.97± 1.00
6 months
GroupValue95% CI
SMA Visit Intervention Arm4.00± 4.58
9 months
GroupValue95% CI
SMA Visit Intervention Arm2.00± 0.00
12 months
GroupValue95% CI
SMA Visit Intervention Arm1.60± 1.47
15 months
GroupValue95% CI
SMA Visit Intervention Arm2.50± 0.71
18 months
GroupValue95% CI
SMA Visit Intervention Arm1.67± 2.08
Continuous Glucose Monitor Time Above Range (>180 mg/dL) Secondary · baseline, 3 months, 6 months, 9 months, 12 months, 15 months, 18 months

We will look at differences in the percent of time that blood sugar values are above range within subject measures across the SMA intervention and during the follow up period.

baseline
GroupValue95% CI
SMA Visit Intervention Arm78.00± 15.62
3 months
GroupValue95% CI
SMA Visit Intervention Arm80.77± 10.51
6 months
GroupValue95% CI
SMA Visit Intervention Arm72.33± 8.33
9 months
GroupValue95% CI
SMA Visit Intervention Arm69.00± 5.66
12 months
GroupValue95% CI
SMA Visit Intervention Arm61.33± 20.03
15 months
GroupValue95% CI
SMA Visit Intervention Arm60.00± 4.24
18 months
GroupValue95% CI
SMA Visit Intervention Arm71.00± 11.53
Continuous Glucose Monitor Mean Sensor Glucose Secondary · baseline, 3 months, 6 months, 9 months, 12 months, 15 months, 18 months

We will look at differences in the mean sensor glucose values within subject measures across the SMA intervention and during the follow up period.

baseline
GroupValue95% CI
SMA Visit Intervention Arm247.75± 17.75
3 months
GroupValue95% CI
SMA Visit Intervention Arm259.25± 35.51
6 months
GroupValue95% CI
SMA Visit Intervention Arm245.33± 13.05
9 months
GroupValue95% CI
SMA Visit Intervention Arm241.50± 3.54
12 months
GroupValue95% CI
SMA Visit Intervention Arm239.00± 30.51
15 months
GroupValue95% CI
SMA Visit Intervention Arm219.67± 15.82
18 months
GroupValue95% CI
SMA Visit Intervention Arm256.67± 47.51
Continuous Glucose Monitor Coefficient of Variation Secondary · baseline, 3 months, 6 months, 9 months, 12 months, 15 months, 18 months

We will look at differences in the coefficient of variation values within subject measures across the SMA intervention and during the follow up period.

baseline
GroupValue95% CI
SMA Visit Intervention Arm41.40± 7.38
3 months
GroupValue95% CI
SMA Visit Intervention Arm30.80± 7.75
6 months
GroupValue95% CI
SMA Visit Intervention Arm41.47± 12.52
9 months
GroupValue95% CI
SMA Visit Intervention Arm42.30± 4.67
12 months
GroupValue95% CI
SMA Visit Intervention Arm43.30± 9.36
15 months
GroupValue95% CI
SMA Visit Intervention Arm44.85± 3.61
18 months
GroupValue95% CI
SMA Visit Intervention Arm39.40± 5.63
Continuous Glucose Monitor Wear Time Secondary · baseline, 3 months, 6 months, 9 months, 12 months, 15 months, 18 months

We will look at differences in percent CGM wear time within subject measures across the SMA intervention and during the follow up period.

baseline
GroupValue95% CI
SMA Visit Intervention Arm63.40± 16.75
3 months
GroupValue95% CI
SMA Visit Intervention Arm67.33± 19.79
6 months
GroupValue95% CI
SMA Visit Intervention Arm64.33± 44.84
9 months
GroupValue95% CI
SMA Visit Intervention Arm89.50± 4.95
12 months
GroupValue95% CI
SMA Visit Intervention Arm74.00± 27.07
15 months
GroupValue95% CI
SMA Visit Intervention Arm71.13± 18.80
18 months
GroupValue95% CI
SMA Visit Intervention Arm65.90± 23.08
Episodes of Diabetic Ketoacidosis (DKA) Secondary · baseline, 3 months, 6 months, 9 months, 12 months, 15 months, 18 months

We will look at differences in number of episodes of DKA since the last study visit within subject measures across the SMA intervention and during the follow up period.

baseline
GroupValue95% CI
SMA Visit Intervention Arm0± 0
3 months
GroupValue95% CI
SMA Visit Intervention Arm0± 0
6 months
GroupValue95% CI
SMA Visit Intervention Arm0± 0
9 months
GroupValue95% CI
SMA Visit Intervention Arm0± 0
12 months
GroupValue95% CI
SMA Visit Intervention Arm0± 0
15 months
GroupValue95% CI
SMA Visit Intervention Arm0± 0
18 months
GroupValue95% CI
SMA Visit Intervention Arm0± 0
Episodes of Severe Hypoglycemia Secondary · baseline, 3 months, 6 months, 9 months, 12 months, 15 months, 18 months

We will look at differences in number of episodes of severe hypoglycemia since the last study visit within subject measures across the SMA intervention and during the follow up period.

baseline
GroupValue95% CI
SMA Visit Intervention Arm0± 0
3 months
GroupValue95% CI
SMA Visit Intervention Arm0± 0
6 months
GroupValue95% CI
SMA Visit Intervention Arm0± 0
9 months
GroupValue95% CI
SMA Visit Intervention Arm0± 0
12 months
GroupValue95% CI
SMA Visit Intervention Arm0± 0
15 months
GroupValue95% CI
SMA Visit Intervention Arm0± 0
18 months
GroupValue95% CI
SMA Visit Intervention Arm0± 0

Sponsor's own description

The investigators propose to conduct a pilot prospective cohort study to assess the impact of shared medical appointments (SMA) visits in underserved youth with poorly controlled type 1 diabetes (T1D). The trial will employ an enrollment visit, SMA visits every 3 months over a 12 month study period, followed by a 6-month observational period to assess feasibility and acceptability of SMA and the impact on glycemic control, self-management skills, and health related quality of life.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Applying the use of shared medical appointments (SMAs) to improve continuous glucose monitor (CGM) use, glycemic control, and quality of life in marginalized youth with type 1 diabetes: Study protocol for a pilot prospective cohort study.
    Grundman JB, Majidi S, Perkins A, Streisand R, et al · · 2023 · cited 3× · PMID 36698741 · DOI 10.1016/j.conctc.2023.101067

Verify or expand the search:

Other recruiting trials for Type 1 Diabetes

Currently open trials in the same condition.

Other Children's National Research Institute trials

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Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05431686.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing