NCT05427539 is a NA clinical trial of TEST LENS in Ocular Physiology, sponsored by Johnson & Johnson Vision Care, Inc..

Who is sponsoring NCT05427539?

NCT05427539 is sponsored by Johnson & Johnson Vision Care, Inc..

What drugs are being tested in NCT05427539?

Interventions in NCT05427539: TEST LENS, CONTROL LENS.

What condition does NCT05427539 study?

NCT05427539 studies Ocular Physiology.

Is NCT05427539 still recruiting?

NCT05427539 is currently completed. Last updated 2 October 2023.

Are results published for NCT05427539?

Yes — primary outcome results have been posted to ClinicalTrials.gov. See the outcomes section above for details.

Last reviewed 2023-10-02 · How we verify

NCT05427539

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Feasibility Evaluation of Daily Disposable Toric Soft Contact Lenses Manufactured With an Alternative Hydration Process

Completed NA Results posted Last updated 2 October 2023

What this trial tests

NA trial testing TEST LENS in Ocular Physiology in 66 participants. Completed in 30 September 2022.

Timeline

12 July 2022

Primary endpoint
30 September 2022

30 September 2022

Quick facts

Lead sponsor	Johnson & Johnson Vision Care, Inc.
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	crossover
Masking	double
Primary purpose	treatment
Enrollment	66
Start date	12 July 2022
Primary completion	30 September 2022
Estimated completion	30 September 2022
Sites	6 locations across United States

Drugs / interventions tested

TEST LENS
CONTROL LENS

Conditions studied

Ocular Physiology — all drugs for Ocular Physiology →

Sponsor

Johnson & Johnson Vision Care, Inc. — full company profile →

Who can join

Adults 18 to 39, any sex, with Ocular Physiology. Patients with the condition only — healthy volunteers not accepted.

Results — posted to ClinicalTrials.gov

Per-arm endpoint measurements with 95% confidence intervals where reported. Source: trial results section.

Proportion of Eyes With Grade 3 or Higher Slit Lamp Findings Primary · Up to 1-Week Follow-up

Slit Lamp Findings (SLF) were assessed using a biomicroscope and was graded using the FDA grading scale (Grade: 0, 1,2, 3 and 4) with grade 0 represents the absence of findings and 1 to 4 representing successively worse findings (i.e. Grade 1 = trace, Grade 2 = Mild, Grade 3 = moderate and Grade 4 = severe). This was performed on each subject eye at every study visit (baseline, unscheduled visits and 1-week follow-up). The data was then dichotomized into two groups. Those with grade 3 or higher and those with grade 2 or lower. The proportion of eyes with SLF with grade 3 or higher was reported

Group	Value	95% CI
Senofilcon A Manufactured With PG Hydration	0
Senofilcon A Manufactured With IPA Hydration	0

Sponsor's own description

This is a bilateral wear, dispensing, randomized, controlled, double-masked, 2-sequence × 2-period crossover study to evaluate ocular physiology following approximately one week of contact lens wear.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

Other trials of TEST LENS

Trials testing the same drug.

NCT05480514 — Clinical Evaluation of Daily Disposable Etafilcon A Cosmetic Contact Lenses (2022) · NA · completed
NCT05502289 — Clinical Evaluation of Delefilcon A and Verofilcon A Daily Disposable Toric Soft Contact Lenses Over One Week of Wear · NA · completed

Other Johnson & Johnson Vision Care, Inc. trials

Trials by the same sponsor.

NCT07443215 — Evaluation of Effect of Scatter on Visual Performance · NA · recruiting
NCT07174596 — Evaluation of Approved Contact Lenses · NA · completed
NCT07076160 — Pilot Dispensing Study of Two Marketed Daily Disposable Multifocal Contact Lenses · NA · completed
NCT06967129 — Evaluation of Daily Disposable Toric Soft Lenses Manufactured With an Alternative Hydration Process · NA · completed
NCT06864858 — Clinical Evaluation of Two Cosmetic Contact Lenses · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05427539 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Johnson & Johnson Vision Care, Inc.
Last refreshed: 2 October 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05427539.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing