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NCT05425888

Functional and Proprioceptive Status in Patients With Hemophilic Ankle Arthropathy

Completed Last updated 9 February 2024
What this trial tests

trial testing Hemophilia group in Haemophilia in 32 participants. Completed in 23 December 2022.

Timeline
22 June 2022
Primary endpoint
18 November 2022
23 December 2022

Quick facts

Lead sponsorInvestigación en Hemofilia y Fisioterapia
StatusCompleted
Study typeOBSERVATIONAL
Enrollment32
Start date22 June 2022
Primary completion18 November 2022
Estimated completion23 December 2022
Sites1 location across Spain

Drugs / interventions tested

Conditions studied

Sponsor

Investigación en Hemofilia y Fisioterapia

Who can join

Adults 18 to 45, male only, with Haemophilia. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Introduction: Hemophilic ankle arthropathy is manifested by functional degenerative alterations (muscle strength deficit, mobility and proprioception), intra-articular and chronic pain. Design: Case-control study. Objective: To observe the differences between patients with hemophilic ankle arthropathy and their healthy peers, regarding dorsiflexion, dorsiflexion strength, biomechanical analysis of gait and balance, and functionality. Patients: 10 patients with hemophilic ankle arthropathy and 12 healthy subjects without ankle joint damage. Measurement instruments and study variables: dorsiflexion (range of motion), dorsiflexion strength (dynamometry), biomechanical analysis of gait and balance (RS SCAN® model platform), and functionality (2 Minute Walk Test). Expected results: Analyze the main differences and their relationship based on the clinical and independent variables of patients with hemophilia, compared to their healthy peers.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Stability, Balance, and Physical Variables in Patients with Bilateral Hemophilic Arthropathy of the Ankle versus Their Healthy Peers: A Case-Control Study.
    Truque-Díaz C, Meroño-Gallut J, Molina-García C, Cuesta-Barriuso R, et al · · 2024 · cited 2× · PMID 39202791 · DOI 10.3390/life14081051

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