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NCT05423704
Feasibility of Patient Selection and Treatment of Head-neck Cancer With Proton Therapy in Denmark
NA trial testing Proton radiotherapy in Head-and-neck Cancer in 63 participants. Participants enrolled and being followed up; not accepting new ones.
14 November 2021
Quick facts
| Lead sponsor | Danish Head and Neck Cancer Group |
|---|---|
| Phase | NA |
| Status | Active, enrolled |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 63 |
| Start date | 20 May 2019 |
| Primary completion | 14 November 2021 |
| Estimated completion | 14 May 2026 |
| Sites | 7 locations across Denmark |
Drugs / interventions tested
- Proton radiotherapy
Conditions studied
- Head-and-neck Cancer — all drugs for Head-and-neck Cancer →
Sponsor
Danish Head and Neck Cancer Group
Who can join
18 and older, any sex, with Head-and-neck Cancer. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
A study to investigate feasibility of local selection of patients with squamous cell carcinoma of the pharynx or larynx using anticipated benefit of proton radiotherapy in reducing the risk of late dysphagia or xerostomia.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Acute toxicities in proton therapy for head and neck cancer - A matched analysis of the DAHANCA 35 feasibility study.
Nowicka-Matus K, Friborg J, Hansen CR, Bernsdorf M, et al · · 2024 · cited 1× · PMID 39189000 · DOI 10.1016/j.ctro.2024.100835 -
Envisioning an Italian Head and Neck Proton Therapy Model-Based Selection: Challenge and Opportunity.
Fontana G, Pepa M, Camarda AM, Strikchani M, et al · · 2025 · PMID 40230401 · DOI 10.1016/j.ijpt.2025.100745
Verify or expand the search:
- PubMed search for NCT05423704
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Trials testing the same drug.
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- NCT06677879 — A Prospective Cohort Study of Proton and Photon Therapy for Left-sided Breast Cancer. · Phase 2 · recruiting
- NCT06311968 — The Clinical Study of Post-operative Proton Radiotherapy for Thymus Tumor · Phase 2 · recruiting
- NCT06133062 — Atezolizumab and Bevacizumab With Proton Radiotherapy for Unresectable Hepatocellular Carcinoma · Phase 2 · recruiting
Other Danish Head and Neck Cancer Group trials
Trials by the same sponsor.
- NCT03981068 — DAHANCA 37. Re-irradiation With Proton Radiotherapy · NA · unknown
- NCT05289336 — DAHANCA 27 Transoral Laser Microsurgery for T1a Glottic Cancer · Phase 2 · unknown
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05423704 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Danish Head and Neck Cancer Group
- Last refreshed: 21 June 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05423704.
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