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NCT05423002: CONE
Effect of Different Color Lights on the Internal Clock and Alertness in Humans
NA trial testing Flickering light stimuli in Light Flashing in 68 participants. Status unknown.
15 March 2023
Quick facts
| Lead sponsor | University of Basel |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | crossover |
| Masking | single |
| Primary purpose | basic science |
| Enrollment | 68 |
| Start date | 20 June 2022 |
| Primary completion | 15 March 2023 |
| Estimated completion | 15 September 2023 |
| Sites | 1 location across Switzerland |
Drugs / interventions tested
- Flickering light stimuli
- Constant light stimuli
- Dim light
Conditions studied
- Light Flashing — all drugs for Light Flashing →
Sponsor
University of Basel
Who can join
Adults 18 to 35, any sex, with Light Flashing. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The main aim of this study is to investigate the effects of cone-modulated light emitted from a visual display on human circadian physiology and cognitive performance in the evening.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Sex and Seasonal Variations in Melatonin Suppression and Alerting Response to Light.
Fazlali F, Lazar R, Yahya F, Stefani O, et al · · 2025 · cited 3× · PMID 41230024 · DOI 10.1210/jendso/bvaf155 -
Lack of strong evidence for cone photoreceptors' contribution to human melatonin suppression and alerting response to light.
Fazlali F, Lazar R, Yahya F, Epple C, et al · · 2025 · cited 3× · PMID 40687802 · DOI 10.1016/j.isci.2025.112983
Verify or expand the search:
- PubMed search for NCT05423002
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05423002 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Basel
- Last refreshed: 21 June 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05423002.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing