NCT05421728 (ENACT) is a NA clinical trial of ENACT group visit in Advance Care Planning, sponsored by University of Colorado, Denver.

Who is sponsoring NCT05421728?

NCT05421728 is sponsored by University of Colorado, Denver.

What drugs are being tested in NCT05421728?

Interventions in NCT05421728: ENACT group visit, Mailed Resources.

What condition does NCT05421728 study?

NCT05421728 studies Advance Care Planning, Primary Health Care.

Is NCT05421728 still recruiting?

NCT05421728 is currently active, enrolled. Last updated 26 September 2025.

Last reviewed 2025-09-26 · How we verify

NCT05421728: ENACT

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Effectiveness of Engaging in Advance Care Planning Talks (ENACT) Group Visits in Primary Care for Older Adults With and Without Alzheimer's Disease

Active, enrolled NA Last updated 26 September 2025

What this trial tests

NA trial testing ENACT group visit in Advance Care Planning in 516 participants. Participants enrolled and being followed up; not accepting new ones.

Timeline

26 July 2022

Primary endpoint
1 May 2027

1 May 2027

Quick facts

Lead sponsor	University of Colorado, Denver
Phase	NA
Status	Active, enrolled
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	prevention
Enrollment	516
Start date	26 July 2022
Primary completion	1 May 2027
Estimated completion	1 May 2027
Sites	8 locations across United States

Drugs / interventions tested

ENACT group visit
Mailed Resources

Conditions studied

Advance Care Planning — all drugs for Advance Care Planning →
Primary Health Care — all drugs for Primary Health Care →

Sponsor

University of Colorado, Denver

Who can join

18 and older, any sex, with Advance Care Planning or Primary Health Care. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The main goal of the ENACT (ENgaging in Advance Care planning Talks) Group Visit intervention is to integrate a patient-centered advance care planning process into primary care, ultimately helping patients to receive medical care that is aligned with their values. The ENACT Group Visit intervention involves two group discussions about advance care planning with 8-10 patients who meet for 2-hour sessions, one month apart, facilitated by a geriatrician and a social worker. This study will compare the ENACT Group Visit intervention to mailed advance care planning materials.

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

Overcoming Barriers to Engaging Latino Older Adults in an Advance Care Planning Clinical Trial: Perspectives for Researchers and Funders.
Farro SA, Mino I, Lum HD, Kielty T, et al · · 2026 · PMID 41173512 · DOI 10.1177/10966218251391030
Engaging English- and Spanish-speaking older adults with and without possible cognitive impairment in advance care planning group visits: protocol for the ENgaging in Advance Care Planning Talks (ENACT) randomized controlled trial.
Farro SA, Juarez-Colunga E, Patel C, Bettcher BM, et al · · 2025 · PMID 40999430 · DOI 10.1186/s13063-025-08964-x
Engaging English- and Spanish-speaking older adults with and without possible cognitive impairment in advance care planning group visits: Protocol for the ENgaging in Advance Care Planning Talks (ENACT) Randomized Controlled Trial
Lum H, Farro S, Juarez-Colunga E, Patel C, et al · · 2025 · DOI 10.21203/rs.3.rs-6560971/v1

Verify or expand the search:

Other trials of ENACT group visit

Trials testing the same drug.

NCT03141242 — ENgaging in Advance Care Planning Talks Group Visit Intervention · NA · completed

Other recruiting trials for Advance Care Planning

Currently open trials in the same condition.

NCT07235839 — The Impact of an Advance Care Planning Game on Life-Sustaining Treatment Preferences, Depression, and Hope in Older Adul · NA · active not recruiting
NCT07134881 — Navigating Advanced Illness Goals And Treatment With Digital Engagement (NAVIGATE) · NA · recruiting
NCT06538493 — Jumpstarting Advance Care Planning With ANAI People · NA · recruiting
NCT06731361 — Improved Prescribing for Older Nursing Home Patients · NA · recruiting
NCT06376799 — Which Health-care Professional(s) to Talk About Advance Care Planning ? · recruiting

Other University of Colorado, Denver trials

Trials by the same sponsor.

NCT07292285 — The Surveillance Nonoperative Watch & Wait (SNOWW) Rectal Cancer Trial. · not yet recruiting
NCT07021937 — Brain Plasticity and GLP-1 Receptor Agonist Treatment for Obesity · Phase 3 · not yet recruiting
NCT07453732 — Banana Leaves as a Wound Dressing for Partial Thickness Second Degree Burns in Adult Patients. · NA · not yet recruiting
NCT07038278 — 5-AminoLevulinic Acid Aided Resection Margins in Sarcoma · EARLY_PHASE1 · not yet recruiting
NCT07279558 — Cannabidiol and Alcohol Use Disorder Phenotypes · Phase 2 · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05421728 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of Colorado, Denver
Last refreshed: 26 September 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05421728.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing