NCT05418452 (MF) is a Phase 3 clinical trial of Metformin in Horizontal Ridge Deficiency, sponsored by Al-Azhar University.

Who is sponsoring NCT05418452?

NCT05418452 is sponsored by Al-Azhar University.

What drugs are being tested in NCT05418452?

Interventions in NCT05418452: Metformin.

What condition does NCT05418452 study?

NCT05418452 studies Horizontal Ridge Deficiency.

Is NCT05418452 still recruiting?

NCT05418452 is currently status unknown. Last updated 14 June 2022.

Last reviewed 2022-06-14 · How we verify

NCT05418452: MF

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Efficacy of 1% Metformin Gel Mixed With PRF in Augmenting Narrow Ridge

Status unknown Phase 3 Last updated 14 June 2022

What this trial tests

Phase 3 trial testing Metformin in Horizontal Ridge Deficiency in 2 participants. Status unknown.

Timeline

15 June 2022

Primary endpoint
15 June 2023

15 June 2023

Quick facts

Lead sponsor	Al-Azhar University
Phase	Phase 3
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	quadruple
Primary purpose	other
Enrollment	2
Start date	15 June 2022
Primary completion	15 June 2023
Estimated completion	15 June 2023
Sites	1 location across Egypt

Drugs / interventions tested

Metformin (metformin) — full drug profile →

Conditions studied

Horizontal Ridge Deficiency — all drugs for Horizontal Ridge Deficiency →

Sponsor

Al-Azhar University

Who can join

Adults 20 to 45, any sex, with Horizontal Ridge Deficiency. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This study aimed to evaluate the efficacy of 1% metformin gel mixed with PRF, in horizontal ridge augmentation with the split-crest technique, for implant placement.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

Verify or expand the search:

Other trials of Metformin

Trials testing the same drug.

NCT07275359 — Investigating Senolytic Properties in Pulmonary Rehabilitation and Metformin in COPD Exacerbations · Phase 1 · not yet recruiting
NCT07520110 — Metformin to Attenuate Progressive Respiratory Decline in Idiopathic Pulmonary Fibrosis · Phase 3 · not yet recruiting
NCT07007221 — Clinical Trials to Evaluate Metformin to Treat Depression in People Living With HIV · Phase 2 · not yet recruiting
NCT07585396 — Inositol in Letrozol Resistant PCOS Women · Phase 2, PHASE3 · not yet recruiting
NCT07226453 — Target Validation and Efficacy of Metformin in Patients With Posterior Fossa Group A (PFA) Ependymoma · Phase 2 · not yet recruiting

Other recruiting trials for Horizontal Ridge Deficiency

Currently open trials in the same condition.

NCT07082244 — Implant Phenotype Modification Via GBR and ADM · NA · recruiting
NCT07056920 — Evaluation of Horizontal Bone Gain of Ridge Augmentation Using Customized Porous Zirconia Shell. · NA · recruiting
NCT06529653 — Ridge Splitting Using Autogenous Bone Wedge Versus the Conventional Intercortical Augmentation Technique in Horizontally · NA · recruiting

Other Al-Azhar University trials

Trials by the same sponsor.

NCT06489327 — Comparing Two Doses of Oral Melatonin as Premedication in Children Undergoing Surgery · NA · recruiting
NCT07327918 — Effect of Epidural Needle Injection on Catheter Placement Success During Painless Labour · Phase 3 · not yet recruiting
NCT07500194 — Quad Helix vs RME for Posterior Cross-bite in Egyptian Children · NA · not yet recruiting
NCT07360756 — Ultrasonographic ONSD as a Predictor of PDPH in Spinal Anesthesia for Cesarean Delivery · not yet recruiting
NCT07343570 — Comparison of Quadratus Lumborum and Combined Groin Nerve Blocks for Postoperative Analgesia After Open Inguinal Hernia · Phase 3 · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05418452 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Al-Azhar University
Last refreshed: 14 June 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05418452.

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