Who is sponsoring NCT05413512?

NCT05413512 is sponsored by Baylor University.

What drugs are being tested in NCT05413512?

Interventions in NCT05413512: Acute psychological stress.

What condition does NCT05413512 study?

NCT05413512 studies Acute Psychological Stress.

Is NCT05413512 still recruiting?

NCT05413512 is currently completed. Last updated 24 June 2025.

Are results published for NCT05413512?

Yes — primary outcome results have been posted to ClinicalTrials.gov. See the outcomes section above for details.

Last reviewed 2025-06-24 · How we verify

NCT05413512

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Stressor-evoked Brain and Cardiovascular Responses to Acute Psychological Stress

Completed NA Results posted Last updated 24 June 2025

What this trial tests

NA trial testing Acute psychological stress in Acute Psychological Stress in 170 participants. Completed in 30 September 2021.

Timeline

2 March 2020

Primary endpoint
30 September 2021

30 September 2021

Quick facts

Lead sponsor	Baylor University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	basic science
Enrollment	170
Start date	2 March 2020
Primary completion	30 September 2021
Estimated completion	30 September 2021
Sites	1 location across United States

Drugs / interventions tested

Acute psychological stress

Conditions studied

Acute Psychological Stress — all drugs for Acute Psychological Stress →

Sponsor

Baylor University

Who can join

Adults 18 to 30, any sex, with Acute Psychological Stress. Patients with the condition only — healthy volunteers not accepted.

Results — posted to ClinicalTrials.gov

Per-arm endpoint measurements with 95% confidence intervals where reported. Source: trial results section.

Stressor-evoked Oxygen Consumption in mL/(kg·Min) (Stress - Baseline) Primary · 18 minutes (approximately 9 minutes for each task)

Stressor-evoked oxygen consumption. (Oxygen consumption during acute psychological stress task - Oxygen consumption during resting baseline).

Stroop task

Group	Value	95% CI
Acute Psychological Stress Task	0.265	± 0.452

MSIT task

Group	Value	95% CI
Acute Psychological Stress Task	0.287	± 0.431

Heart Rate (Bpm) Measured by Electrocardiogram Primary · 18 minutes (approximately 9 minutes for each stress task)

Stressor-evoked heart rate. (Heart rate during acute psychological stress task - Heart rate during resting baseline).

Stroop task

Group	Value	95% CI
Acute Psychological Stress	4.926	± 7.456

MSIT

Group	Value	95% CI
Acute Psychological Stress	2.826	± 6.317

Neural Activity Measured by fMRI Primary · 18 minutes (approximately 9 minutes for each stress task).

Stressor-evoked neural activity. Incongruent-vs-Congruent t at the group-level, filtered at 0.05 after FDR correction and with a cluster extent of 50 voxels.

L Parietal_inf (stroop)

Group	Value	95% CI
Acute Psychological Stress	0.71	± 0.41

R Angular (stroop)

Group	Value	95% CI
Acute Psychological Stress	0.54	± 0.35

R Supp_Motor_Area (stroop)

Group	Value	95% CI
Acute Psychological Stress	1	± 0.65

L Frontal_Inf_Tri (stroop)

Group	Value	95% CI
Acute Psychological Stress	0.85	± 0.56

L Parietal_Inf2 (stroop)

Group	Value	95% CI
Acute Psychological Stress	0.66	± 0.45

R Insula (stroop)

Group	Value	95% CI
Acute Psychological Stress	0.70	± 0.50

R Frontal_Inf_Oper (stroop)

Group	Value	95% CI
Acute Psychological Stress	0.76	± 0.60

R Vermis (stroop)

Group	Value	95% CI
Acute Psychological Stress	0.84	± 0.68

Sponsor's own description

The present study will examine cardiovascular, metabolic, and neural responses to acute psychological stress using a cross-sectional approach.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

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Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05413512 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Baylor University
Last refreshed: 24 June 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05413512.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing