NCT05411562 (NOSO-COVID) is a clinical trial of SARS-CoV-2 genomic sequencing in COVID-19, sponsored by Centre hospitalier de l'Université de Montréal (CHUM).

Who is sponsoring NCT05411562?

NCT05411562 is sponsored by Centre hospitalier de l'Université de Montréal (CHUM).

What drugs are being tested in NCT05411562?

Interventions in NCT05411562: SARS-CoV-2 genomic sequencing.

What condition does NCT05411562 study?

NCT05411562 studies COVID-19, Molecular Sequence Variation, Nosocomial Infection.

Is NCT05411562 still recruiting?

NCT05411562 is currently completed. Last updated 19 September 2024.

Last reviewed 2024-09-19 · How we verify

NCT05411562: NOSO-COVID

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

COVID-19 Genomic Sequencing for Nosocomial Outbreak Investigations

Completed Last updated 19 September 2024

What this trial tests

trial testing SARS-CoV-2 genomic sequencing in COVID-19 in 150 participants. Completed in 31 December 2023.

Timeline

9 November 2020

Primary endpoint
31 December 2023

31 December 2023

Quick facts

Lead sponsor	Centre hospitalier de l'Université de Montréal (CHUM)
Status	Completed
Study type	OBSERVATIONAL
Enrollment	150
Start date	9 November 2020
Primary completion	31 December 2023
Estimated completion	31 December 2023
Sites	1 location across Canada

Drugs / interventions tested

SARS-CoV-2 genomic sequencing

Conditions studied

COVID-19 — all drugs for COVID-19 →
Molecular Sequence Variation — all drugs for Molecular Sequence Variation →
Nosocomial Infection — all drugs for Nosocomial Infection →

Sponsor

Centre hospitalier de l'Université de Montréal (CHUM)

Who can join

Adults 18 to 100, any sex, with COVID-19 or Molecular Sequence Variation. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This is a tertiary care hospital-based prospective molecular epidemiology study in Montreal, Canada. When nosocomial transmission was suspected by local infection control teams' investigations, SARS-CoV-2 viral genomic sequencing was performed locally for all putative outbreak cases and contemporary controls. Molecular and conventional epidemiology data were confronted in real time to improve understanding of COVID-19 transmission and reinforce or adapt prevention measures.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

On-demand, hospital-based, severe acute respiratory coronavirus virus 2 (SARS-CoV-2) genomic epidemiology to support nosocomial outbreak investigations: A prospective molecular epidemiology study.
Benoit P, Jolicoeur G, Point F, Soucy C, et al · · 2023 · cited 2× · PMID 36960087 · DOI 10.1017/ash.2023.119
On-Demand Hospital-Based SARS-CoV-2 Genomic Epidemiology to Support Nosocomial Outbreak Investigations: A Prospective Molecular Epidemiology Study in Montreal
Benoit P, Jolicoeur G, Point F, Normand K, et al · · 2022 · DOI 10.2139/ssrn.4199208

Verify or expand the search:

Other recruiting trials for COVID-19

Currently open trials in the same condition.

NCT07183709 — Safety and Immunogenicity Trial of PepGNP-COVID19 Vaccine in Adults · Phase 1 · active not recruiting
NCT07300839 — A Study to Learn About a COVID-19 Vaccine in Healthy Adults 50 Through 64 Years of Age · Phase 3 · active not recruiting
NCT07221162 — A Safety and Immunogenicity Trial of Boost-2867 Vaccine, Via Intranasal and Intramuscular Routes · Phase 1 · recruiting
NCT07215520 — Safety and Tolerability of a Newcastle Disease Virus-Based Mucosal COVID-19 Vaccine in Previously Vaccinated Adults · Phase 2 · recruiting
NCT07222384 — A Study to Learn About BNT162b2 (LP.8.1)-Adapted Vaccine Against SARS-CoV-2 in Children 5 Through 11 Years of Age That A · Phase 3 · active not recruiting

Other Centre hospitalier de l'Université de Montréal (CHUM) trials

Trials by the same sponsor.

NCT06735638 — Outside the Cage (OTC) Robotic Esophagectomy · Phase 1 · not yet recruiting
NCT07533253 — Rescue Distal Thrombectomy in Treatment for Persistent Distal Occlusions · NA · not yet recruiting
NCT05225272 — Effectiveness of an Enhanced Recovery After Surgery Protocol in Patients Undergoing On-pump Cardiac Surgery · not yet recruiting
NCT07497061 — Comparison of Two Surgical Techniques for the Treatment of Trigger Fingers: Longitudinal Opening Versus Complete A1 Pull · NA · not yet recruiting
NCT07196410 — KAN-004 for Immune-Related Diarrhea or Colitis · Phase 1 · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05411562 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Centre hospitalier de l'Université de Montréal (CHUM)
Last refreshed: 19 September 2024

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05411562.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing