NCT05410665 is a clinical trial of Standard treatments for sepsis in Sepsis, sponsored by Nanjing First Hospital, Nanjing Medical University.

Who is sponsoring NCT05410665?

NCT05410665 is sponsored by Nanjing First Hospital, Nanjing Medical University.

What drugs are being tested in NCT05410665?

Interventions in NCT05410665: Standard treatments for sepsis.

What condition does NCT05410665 study?

NCT05410665 studies Sepsis, Intestinal Mucosal Barrier, Ferroptosis.

Is NCT05410665 still recruiting?

NCT05410665 is currently status unknown. Last updated 8 June 2022.

Last reviewed 2022-06-08 · How we verify

NCT05410665

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

The Roles of IL-9/E-cadherin and Ferroptosis in Intestinal Mucosal Barrier Injury in Sepsis

Status unknown Last updated 8 June 2022

What this trial tests

trial testing Standard treatments for sepsis in Sepsis in 100 participants. Status unknown.

Timeline

31 May 2022

Primary endpoint
31 December 2023

30 June 2024

Quick facts

Lead sponsor	Nanjing First Hospital, Nanjing Medical University
Status	Status unknown
Study type	OBSERVATIONAL
Enrollment	100
Start date	31 May 2022
Primary completion	31 December 2023
Estimated completion	30 June 2024
Sites	1 location across China

Drugs / interventions tested

Standard treatments for sepsis

Conditions studied

Sepsis — all drugs for Sepsis →
Intestinal Mucosal Barrier — all drugs for Intestinal Mucosal Barrier →
Ferroptosis — all drugs for Ferroptosis →

Sponsor

Nanjing First Hospital, Nanjing Medical University

Who can join

Adults 18 to 80, any sex, with Sepsis or Intestinal Mucosal Barrier. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The investigators aim to evaluate the roles of IL-9/E-cadheirin and ferroptosis in the intestinal mucosal barrier injury of sepsis. The results of this study would lay the foundation for revealing the mechanisms of EEN improving immune imbalance of sepsis and provide a new idea to the early treatment of sepsis.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Mitochondria-associated programmed cell death as a therapeutic target for age-related disease.
Nguyen TT, Wei S, Nguyen TH, Jo Y, et al · · 2023 · cited 221× · PMID 37612409 · DOI 10.1038/s12276-023-01046-5
In defence of ferroptosis.
Alves F, Lane D, Nguyen TPM, Bush AI, et al · · 2025 · cited 75× · PMID 39746918 · DOI 10.1038/s41392-024-02088-5

Verify or expand the search:

Other recruiting trials for Sepsis

Currently open trials in the same condition.

NCT07507877 — Infraclavicular Axillary Vein Collapsibility Index as a Predictor of Fluid Responsiveness · recruiting
NCT07154615 — Assessing Immune Dysfunction in Sepsis · recruiting
NCT07419802 — OxiCLEAR (Oxiris Cytokines and Endotoxin Adsorption Rate) Study · recruiting
NCT07351344 — African Survey on Sepsis Knowledge (ASK) · recruiting
NCT07448805 — Accuracy and Safety of the Syai Tag System for Continuous Glucose Monitoring in Intensive Internal Care Unit · NA · recruiting

Other Nanjing First Hospital, Nanjing Medical University trials

Trials by the same sponsor.

NCT07349979 — PCI With Guideline-Directed Medical Therapy for HFpEF Patients With Ischemic Cardiomyopathy · NA · not yet recruiting
NCT07505056 — Jianpi Lishi Jiedu Granules for Prevention of Postoperative Recurrence in Colorectal Advanced Adenomas · Phase 3 · not yet recruiting
NCT07397234 — Thyroid Cartilage Plane VS Superior Laryngeal Nerve Space Block in Awake Tracheal Intubation · NA · not yet recruiting
NCT07455448 — Antibiotic Resistance of Helicobacter Pylori in Nanjing: A Cross-Sectional Study · completed
NCT07385885 — Ultrasound-guided Non-invasive Simulation in Anesthesia Residency Training · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05410665 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Nanjing First Hospital, Nanjing Medical University
Last refreshed: 8 June 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05410665.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing