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NCT05408117
Impact of Suture Type on Pigment Disturbances in Patients of Skin of Color
NA trial testing 5-0 Polypropylene epidermal suture in Scar in 34 participants. Currently enrolling.
29 August 2026
Quick facts
| Lead sponsor | Melissa Pugliano-Mauro |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 34 |
| Start date | 1 October 2022 |
| Primary completion | 29 August 2026 |
| Estimated completion | 1 October 2026 |
| Sites | 3 locations across United States |
Drugs / interventions tested
- 5-0 Polypropylene epidermal suture
- 5-0 Fast gut epidermal suture
Conditions studied
- Scar — all drugs for Scar →
Sponsor
Melissa Pugliano-Mauro — full company profile →
Who can join
18 and older, any sex, with Scar. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The present study assesses if dissolvable (fast gut) or non-dissolvable (polypropylene) epidermal sutures produce better cosmetic results in terms of dyspigmentation and scarring in patients of skin of color. Through a split-wound study design, patients undergoing standard elliptical excisions at least 3 cm in length will receive each suture type. Measurements of dyspigmentation and scarring will be made at 7 days (for the head and neck), 10 days (for the trunk and extremities), and 3 months for all locations.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT05408117
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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- NCT05478551 — Randomized Controlled Trial Examining the Efficacy of Botulinum Toxin in Biopsy Scar Minimization · Phase 2, PHASE3 · active not recruiting
Other Melissa Pugliano-Mauro trials
Trials by the same sponsor.
- NCT03561376 — Zinc Oxide Versus Petrolatum Following Skin Surgery · EARLY_PHASE1 · recruiting
- NCT03370406 — Intralesional 5-Fluorouracil (5FU), Topical Calcipotriene Treatment for SCC · Phase 1 · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05408117 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Melissa Pugliano-Mauro
- Last refreshed: 8 July 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05408117.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing