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NCT05408000
Comparision of Motor Seizure Duration of Ketofol and Propofol for Electroconvulsive Therapy
NA trial testing ketofol vs propofol in Electroconvulsive Therapy in 54 participants. Completed in 15 June 2021.
15 June 2021
Quick facts
| Lead sponsor | Tribhuvan University Teaching Hospital, Institute Of Medicine. |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | triple |
| Primary purpose | treatment |
| Enrollment | 54 |
| Start date | 1 January 2021 |
| Primary completion | 15 June 2021 |
| Estimated completion | 15 June 2021 |
| Sites | 1 location across Nepal |
Drugs / interventions tested
- ketofol vs propofol — full drug profile →
Conditions studied
- Electroconvulsive Therapy — all drugs for Electroconvulsive Therapy →
Sponsor
Tribhuvan University Teaching Hospital, Institute Of Medicine.
Who can join
Adults 16 to 65, any sex, with Electroconvulsive Therapy. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Propofol is routinely used in our hospital for ECT. It causes hypotension and has anticonvulsant actions. Use of ketofol ( 1:1 combination of ketamine and propofol) during ECT can have longer seizure duration and better hemodynamics than propofol alone which ultimately leads to better therapeutic efficacy. Motor seizure duration of minimum 20-25 seconds is usually recommended for therapeutic efficacy of ECT.Patients planned for electroconvulsive therapy meeting the inclusion criteria and not having exclusion criteria will be randomized into two groups. Group K will receive titrated dose of Ketofol and Group P will receive titrated dose of Propofol for induction of anaesthesia
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT05408000
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other Tribhuvan University Teaching Hospital, Institute Of Medicine. trials
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05408000 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Tribhuvan University Teaching Hospital, Institute Of Medicine.
- Last refreshed: 7 June 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05408000.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing