Last reviewed · How we verify
NCT05402696: SPARC-C
St. Paul's Advanced Resection Center Cohort for Colorectal Neoplasia (SPARC-C)
trial testing Endoscopic tissue resection in Colon Adenoma in 3,500 participants. Currently enrolling.
31 December 2032
Quick facts
| Lead sponsor | University of British Columbia |
|---|---|
| Status | Recruiting now |
| Study type | OBSERVATIONAL |
| Enrollment | 3,500 |
| Start date | 27 June 2022 |
| Primary completion | 31 December 2032 |
| Estimated completion | 31 December 2032 |
| Sites | 3 locations across Canada |
Drugs / interventions tested
- Endoscopic tissue resection
Conditions studied
- Colon Adenoma — all drugs for Colon Adenoma →
- Colon Polyp — all drugs for Colon Polyp →
- Colon Lesion — all drugs for Colon Lesion →
Sponsor
University of British Columbia
Who can join
18 and older, any sex, with Colon Adenoma or Colon Polyp. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The SPARC-C study is a prospective, single-centre observational study of patients referred for the management of large (≥ 20mm) non-pedunculated colorectal polyps (LNPCPs). Patients are managed consistent with current standards of care. Prospectively collected data includes: patient clinicodemographic details, lesion details, procedural details, and clinical outcomes.
Publications & conference data
8 peer-reviewed publications reference this trial (live from Europe PMC):
-
Poster Session I - A164 THE ASSOCIATION OF INFLAMMATORY BOWEL DISEASE WITH CARCINOID TUMORS: A CASE-BASED SYSTEMATIC REVIEW
· 2026 -
Poster Session I - A163 A COLORECTAL CANCER-ASSOCIATED FECAL MIRNOME AND ITS POTENTIAL TO ALTER FUSOBACTERIUM NUCLEATUM AND ESCHERICHIA COLI GENE EXPRESSION
· 2026 -
Poster Session I - A161 G0S2 PROTEIN REGULATES COLON INFLAMMATION AND COLORECTAL CANCER THROUGH PRODUCTION OF BRANCHED-CHAIN FATTY ACIDS
· 2026 -
Poster Session I - A162 COLON-SPECIFIC MINIMALLY INVASIVE ENDOSCOPIC RESECTION OUTCOMES: A PROSPECTIVE MULTICENTER COHORT OF 1000 LARGE NON-PEDUNCULATED COLONIC POLYPS
· 2026 -
UEG Week 2024 Poster Presentations
· 2024 -
A132 A COLON-SPECIFIC SELECTIVE RESECTION ALGORITHM FOR LARGE NON-PEDUNCULATED POLYPS OPTIMIZES EFFICIENCY WITH HIGH TECHNICAL AND CLINICAL SUCCESS: A PROSPECTIVE COHORT STUDY
· 2024 -
A94 PRE-RESECTION OPTICAL EVALUATION RELIABLY DIFFERENTIATES BETWEEN SERRATED AND ADENOMATOUS LARGE NON-PEDUNCULATED COLORECTAL POLYPS
· 2024 -
A133 MARGIN THERMAL ABLATION WITH SNARE-TIP SOFT COAGULATION EFFECTIVELY MITIGATES RECURRENCE AFTER ENDOSCOPIC MUCOSAL RESECTION OF LARGE NON-PEDUNCULATED COLORECTAL POLYPS
· 2024
Verify or expand the search:
- PubMed search for NCT05402696
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Colon Adenoma
Currently open trials in the same condition.
- NCT06550908 — Training Physicians to Differentiate the Paris Classification Using Artificial Colon Polyp Images · NA · recruiting
- NCT07450612 — Liquid Biopsy and Machine Learning for Early Colorectal Cancer, Adenomas, Lynch Cancers, and Residual Disease Detection · recruiting
- NCT05041478 — Cold Snare Endoscopic Mucosal Resection (EMR) vs Cold EMR With Margin Snare Tip Soft Coagulation (STSC) · NA · recruiting
- NCT05355363 — Risk of Metachronous Findings After Detection of Serrated Lesions and High-grade Dysplasia With Surveillance Delay · NA · recruiting
Other University of British Columbia trials
Trials by the same sponsor.
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- NCT07492095 — Leucine Requirements in School-Age Children · NA · not yet recruiting
- NCT07429305 — Combined Tibial Nerve Stimulation and Standing for People With SCI · NA · recruiting
- NCT07519928 — Exploring the Feasibility and Benefits of Implementing Pelvic Floor Muscle Training During Inpatient Rehabilitation for · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05402696 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of British Columbia
- Last refreshed: 9 November 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05402696.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing