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NCT05400707: EMERGE VI-VII
Triage - Symptoms and Other Predictors in an All-comer Emergency Department Population
trial testing Assessment of vital signs in Triage Risk Stratification in 6,467 participants. Currently enrolling.
27 May 2026
Quick facts
| Lead sponsor | University Hospital, Basel, Switzerland |
|---|---|
| Status | Recruiting now |
| Study type | OBSERVATIONAL |
| Enrollment | 6,467 |
| Start date | 17 May 2022 |
| Primary completion | 27 May 2026 |
| Estimated completion | 31 December 2026 |
| Sites | 1 location across Switzerland |
Drugs / interventions tested
- Assessment of vital signs
- Assessment of patient mobility at presentation
- Assessment of level of consciousness by AVPUC scale
- Assessment of symptoms patients presenting when admitted to ED
- Assessment of what matters most in patients of 65 years and older
- Assessment of Decision-making in senior physicians
- Pain Numeric Rating Scale (NRS)
- Clinical Frailty Scale (CFS)
- Peripheral Perfusion Index (PPI)
- Capillary Refill Time (CRT)
- Mottling Score (MS)
- Mental health complaints
- Altered mental status - a vital sign
Conditions studied
- Triage Risk Stratification — all drugs for Triage Risk Stratification →
Sponsor
University Hospital, Basel, Switzerland
Who can join
18 and older, any sex, with Triage Risk Stratification. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study is to evaluate a tool capable of improved risk prediction regarding the 30-day mortality. The primary objective of this study is hospitalization, ICU-admission, morbidity and mortality in correlation with external validation of International Early Warning Score (IEWS) and decision-making processes regarding diagnosis, treatment and disposition in the ED.
Publications & conference data
5 peer-reviewed publications reference this trial (live from Europe PMC):
-
Clinical Frailty Scale at presentation to the emergency department: interrater reliability and use of algorithm-assisted assessment.
Albrecht R, Espejo T, Riedel HB, Nissen SK, et al · · 2024 · cited 14× · PMID 37971677 · DOI 10.1007/s41999-023-00890-y -
Predictive value and interrater reliability of mental status and mobility assessment in the emergency department.
Espejo T, Riedel HB, Messingschlager S, Sonnleitner W, et al · · 2024 · cited 5× · PMID 38369128 · DOI 10.1016/j.clinme.2024.100027 -
Assessing what matters most in older emergency department patients.
Griese JA, Ünlü L, van Oppen J, Bühler N, et al · · 2025 · cited 1× · PMID 41251602 · DOI 10.1093/ageing/afaf334 -
Screening for elder mistreatment in a Swiss emergency department: a prospective cohort study.
Riedel HB, Espejo T, Dreher-Hummel T, Bingisser R, et al · · 2024 · PMID 38875501 · DOI 10.57187/s.3775 -
Clinical Frailty Scale at Presentation to the Emergency Department: Interrater Reliability and Use of Electronic Decision Support
Albrecht R, Espejo T, Riedel HB, Nissen SK, et al · · 2023 · DOI 10.21203/rs.3.rs-3113730/v1
Verify or expand the search:
- PubMed search for NCT05400707
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Assessment of vital signs
Trials testing the same drug.
- NCT03892551 — Triage - Symptoms and Other Predictors in an All-comer Emergency Department Population; (EKBB 236/13) · completed
Other University Hospital, Basel, Switzerland trials
Trials by the same sponsor.
- NCT07444788 — Acute Effects of Intravenous 5-MeO-DMT in Healthy Participants · Phase 1 · recruiting
- NCT07494214 — Acute Analgesic Effects of MDMA on Experimentally Induced Acute Pain, Hyperalgesia and Allodynia in Healthy Participants · Phase 1 · recruiting
- NCT07419048 — Artificial Intelligence or Human Hand? Evaluating Inferior Vena Cava Imaging for Hydration Status · recruiting
- NCT06978777 — Effect of Caffeine on Cold-stimulated Brown Adipose Tissue Activity · NA · recruiting
- NCT07273630 — Effect of Protein Supplementation and Fluid Restriction on Plasma Sodium Levels in Patients Undergoing Pituitary Surgery · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05400707 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University Hospital, Basel, Switzerland
- Last refreshed: 26 January 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05400707.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing