Who is sponsoring NCT05400356?

NCT05400356 is sponsored by West China Hospital.

What drugs are being tested in NCT05400356?

Interventions in NCT05400356: On-pump valve surgery or CABG.

What condition does NCT05400356 study?

NCT05400356 studies On-pump Valve Surgery or CABG.

Is NCT05400356 still recruiting?

NCT05400356 is currently status unknown. Last updated 22 February 2023.

Last reviewed 2023-02-22 · How we verify

NCT05400356: DIMOCS

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Dynamics of Immune Map and Outcomes After On-pump Cardiac Surgery: Protocol for a Prospective Cohort Study

Status unknown Last updated 22 February 2023

What this trial tests

trial testing On-pump valve surgery or CABG in On-pump Valve Surgery or CABG in 120 participants. Status unknown.

Timeline

1 June 2022

Primary endpoint
31 March 2023

31 March 2023

Quick facts

Lead sponsor	West China Hospital
Status	Status unknown
Study type	OBSERVATIONAL
Enrollment	120
Start date	1 June 2022
Primary completion	31 March 2023
Estimated completion	31 March 2023
Sites	1 location across China

Drugs / interventions tested

On-pump valve surgery or CABG

Conditions studied

On-pump Valve Surgery or CABG — all drugs for On-pump Valve Surgery or CABG →

Sponsor

West China Hospital

Who can join

18 and older, any sex, with On-pump Valve Surgery or CABG. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Although systemic inflammatory response induced by cardiopulmonary bypass is believed as one of main reasons for these adverse events, the involved mechanism is still unclear.This cohort study would include patients undergoing on-pump valve surgery or CABG. By detecting the changes of immune cell expression profile and inflammatory related substances in blood, the spatiotemporal change curve of immune function of patients is drawn for avoiding or treating adverse events.

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

Perioperative Profiles of Immune Cells in Patients with Postoperative Delirium After Cardiac Surgery with Cardiopulmonary Bypass.
Wu J, Cheng Z, Liao X, Yang P, et al · · 2025 · cited 1× · PMID 41462974 · DOI 10.3390/biomedicines13122962
Single-cell immune landscape of acute kidney injury after cardiac surgery with cardiopulmonary bypass.
Wang T, Yao Y, Sun J, Wu J, et al · · 2025 · PMID 41199602 · DOI 10.1080/0886022x.2025.2581506
In vitro Validation of a Novel Disposable Remover to Remove Activated Leukocytes Generated During Cardiopulmonary Bypass: A Pilot Study.
Zheng Y, Ran Y, Wu J, Yang P, et al · · 2025 · PMID 40270561 · DOI 10.2147/jir.s503575

Verify or expand the search:

Other West China Hospital trials

Trials by the same sponsor.

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Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05400356 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by West China Hospital
Last refreshed: 22 February 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05400356.

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