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NCT05398068
Effects of Exercise Training on Exercise Capacity and Sleep Quality in Patients With Obesity Hypoventilation Syndrome
NA trial testing Exercises and Diet in Obesity Hypoventilation Syndrome (OHS) in 40 participants. Completed in 7 June 2024.
7 June 2024
Quick facts
| Lead sponsor | Istanbul University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 40 |
| Start date | 15 June 2022 |
| Primary completion | 7 June 2024 |
| Estimated completion | 7 June 2024 |
| Sites | 1 location across Turkey (Türkiye) |
Drugs / interventions tested
- Exercises and Diet
- Diet
Conditions studied
- Obesity Hypoventilation Syndrome (OHS) — all drugs for Obesity Hypoventilation Syndrome (OHS) →
- Hypoventilation — all drugs for Hypoventilation →
- Obesity — all drugs for Obesity →
- Respiration Disorders — all drugs for Respiration Disorders →
Sponsor
Istanbul University
Who can join
18 and older, any sex, with Obesity Hypoventilation Syndrome (OHS) or Hypoventilation. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Obesity Hypoventilation Syndrome is defined as a combination of obesity (BMI ≥ 30 kg/m2) and daytime hypercapnia in arterial blood gas analysis (PaCO2 \> 45 mmHg) without other pathologies that cause hypoventilation. Symptoms seen in individuals diagnosed with OHS are stated as a feeling of suffocation due to apnea, loud snoring, morning headache and excessive daytime sleepiness. Respiratory mechanics, respiratory muscle performance, pulmonary gas exchange, lung functions and exercise capacity parameters are adversely affected in patients. Early treatment is important so that these negative changes do not lead to worse outcomes. Weight control, bariatric surgery, pharmacological treatment and non-invasive mechanical ventilation (NIMV) are included in the treatment program of OHS patients. The effects of exercise on the treatment program of OHS patients are unknown. Considering all the studies in the literature, the primary purpose of this study is to evaluate aerobic and strength training on exercise capacity and sleep quality in patients with hypoventilation syndrome. The secondary aim is to examine the effect of this exercise training on peripheral muscle strength, emotional state, body composition and quality of life parameters. In addition, the researchers believe that this study will form the basis for further scientific studies on OHS and exercise and will make an important contribution to the literature.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT05398068
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- ASCO Meeting Library
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Related trials
Other recruiting trials for Obesity Hypoventilation Syndrome (OHS)
Currently open trials in the same condition.
- NCT07060079 — The Use of Entropy to Assess Sleep Disordered Breathing in Chronic Respiratory Disease · recruiting
- NCT06367686 — Detecting Systemic Carbon Dioxide Levels With a Novel Biosensor · recruiting
- NCT07147153 — Functional Capacity, Sleep Quality, and Cognitive Function in Obesity Hypoventilation Syndrome · recruiting
Other Istanbul University trials
Trials by the same sponsor.
- NCT07472946 — Whole-Body Vibration Exercise in Patients With Parkinson's Disease · NA · not yet recruiting
- NCT07433894 — Scoliosis and Functional Outcomes in Children With Juvenile Idiopathic Arthritis · not yet recruiting
- NCT07420049 — Turkish Adaptation of the CTS-6 Evaluation Tool: A Validation and Reliability Study · not yet recruiting
- NCT07415967 — The Effect of a Dual-Task Technique-Based Exercise Program on Clinical Outcomes in Rotator Cuff Related Shoulder Pain · NA · recruiting
- NCT07473024 — pEEG-Guided Anesthesia and Behavioral Outcomes in Children · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05398068 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Istanbul University
- Last refreshed: 29 August 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05398068.
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