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NCT05397886
Comparison of Remimazolam With Flumazenil vs. Propofol During RFCA for Atrial Fibrillation
NA trial testing Remimazolam Besylate in Recovery in 54 participants. Completed in 25 April 2023.
25 April 2023
Quick facts
| Lead sponsor | Seoul National University Hospital |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | triple |
| Primary purpose | treatment |
| Enrollment | 54 |
| Start date | 2 August 2022 |
| Primary completion | 25 April 2023 |
| Estimated completion | 25 April 2023 |
| Sites | 1 location across South Korea |
Drugs / interventions tested
- Remimazolam Besylate — full drug profile →
- Flumazenil (FLUMAZENIL) — full drug profile →
- Propofol (Propofol) — full drug profile →
Conditions studied
- Recovery — all drugs for Recovery →
Sponsor
Seoul National University Hospital
Who can join
Adults 20 to 75, any sex, with Recovery. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This prospective randomized trial aims to compare recovery time from discontinuation of remimazolam followed by flumazenil administration vs. propofol total intravenous anesthesia as the main general anesthetics during radiofrequency catheter ablation treatment of atrial fibrillation.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Remimazolam-flumazenil provides fast recovery from general anesthesia compared to propofol during radiofrequency catheter ablation of atrial fibrillation.
Lee S, Lee J, Hwang SY, Ju JW, et al · · 2024 · cited 12× · PMID 38831029 · DOI 10.1038/s41598-024-63578-8 -
Comparison of the recovery quality between remimazolam and propofol after general anesthesia: systematic review and a meta-analysis of randomized controlled trials.
Zhu C, Xie R, Qin F, Wang N, et al · · 2024 · cited 2× · PMID 39210920 · DOI 10.7717/peerj.17930
Verify or expand the search:
- PubMed search for NCT05397886
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Remimazolam Besylate
Trials testing the same drug.
- NCT07155265 — REMIMID-ICU: Remimazolam vs Midazolam for Deep Sedation in Hemodynamically Unstable, Mechanically Ventilated Adults · Phase 3 · not yet recruiting
- NCT07045467 — Remimazolam Infusion in Kidney Transplant Patients: A Multicenter Study · Phase 1 · recruiting
- NCT06575530 — Sedation Efficacy and Safety of Remazolam Besylate in Ventilated Surgical Critically Ill Patients · Phase 4 · recruiting
- NCT05453955 — Effect of Remimazolam on Motor Evoked Potential · NA · completed
- NCT05606315 — RemImazolam Besylate for ICU-sedation in Patients With Mechanical Ventilation After Oral and Maxillofacial Surgery · Phase 4 · unknown
Other recruiting trials for Recovery
Currently open trials in the same condition.
- NCT07430865 — The RECOVER Study - Postpartum Recovery of Pelvic Floor Structures and the Impact of Early Rehabilitation · NA · recruiting
- NCT07343219 — Effects of Root Extract Ashwagandha (KSM-66) on Physiological Stress, Perception of Recovery and Muscle Strength in Yout · NA · active not recruiting
- NCT07255131 — The Effectiveness and Efficacy of an Online Cognitive Behavioral Psychotherapeutic Program · NA · recruiting
- NCT05074732 — Dundrum Forensic Redevelopment Evaluation Study: D-FOREST Study. · recruiting
- NCT04549610 — HMB and Exercise-induced Muscle Damage · Phase 2, PHASE3 · recruiting
Other Seoul National University Hospital trials
Trials by the same sponsor.
- NCT07262944 — EOI Block in Otoplasty With Rib Cartilage Graft · NA · recruiting
- NCT07464210 — Nemtabrutinib, Bortezomib, and Rituximab for WM · Phase 2 · not yet recruiting
- NCT07550803 — Effect of Intraoperative Dexamethasone on Early Postoperative Sleep Quality in Patients Undergoing Nasal Surgery · NA · not yet recruiting
- NCT07522138 — Home-based Self-exercise in Patients With Parkinson's Disease: A Feasibility Study · NA · not yet recruiting
- NCT07476651 — Scout Dose of Resin Microspheres · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05397886 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Seoul National University Hospital
- Last refreshed: 22 November 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05397886.
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