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Behavioural Science Messages in Breast Cancer Screening
NA trial testing Behavioural Message in Breast Cancer in 34,047 participants. Completed in 15 January 2023.
| Lead sponsor | Imperial College London |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | screening |
| Enrollment | 34,047 |
| Start date | 15 July 2022 |
| Primary completion | 15 January 2023 |
| Estimated completion | 15 January 2023 |
| Sites | 1 location across United Kingdom |
Imperial College London
Adults 50 to 70, female only, with Breast Cancer. Patients with the condition only — healthy volunteers not accepted.
Per-arm endpoint measurements with 95% confidence intervals where reported. Source: trial results section.
Percentage uptake of breast cancer screening, three months after the initial invitation letter- intention to treat.
| Group | Value | 95% CI |
|---|---|---|
| Usual Care | 2225 | |
| Behavioural Message | 2064 | |
| Behavioural Message + Video | 2137 |
No. of participants taking up breast cancer screening, three months after the initial invitation letter- per protocol
| Group | Value | 95% CI |
|---|---|---|
| Usual Care | 2073 | |
| Behavioural Message | 1899 | |
| Behavioural Message + Video | 1977 |
No. of participants taking up breast cancer screening, three months after the initial invitation letter amongst those from sociodemographic groups (ethnicity) Note there remain 3 trial arms (usual care, behavioural message, behavioural message + video), data represents subgroup analysis dichotomising these arms into white v. non white ethnicity).
| Group | Value | 95% CI |
|---|---|---|
| Usual Care | 1379 | |
| Behavioural Message | 1276 | |
| Behavioural Message + Video | 1303 |
| Group | Value | 95% CI |
|---|---|---|
| Usual Care | 1206 | |
| Behavioural Message | 1194 | |
| Behavioural Message + Video | 1243 |
No. of participants taking up breast cancer screening, three months after the initial invitation letter, amongst those given different invitation types.
| Group | Value | 95% CI |
|---|---|---|
| Usual Care- Open | 4104 | |
| Behavioural Message- Open | 3909 | |
| Behavioural Message + Video- Open | 3978 |
No. of participants taking up breast cancer screening, three months after the initial invitation letter, amongst those with different screening history
| Group | Value | 95% CI |
|---|---|---|
| Usual Care | 406 | |
| Behavioural Message | 379 | |
| Behavioural Message + Video | 394 |
| Group | Value | 95% CI |
|---|---|---|
| Usual Care | 1820 | |
| Behavioural Message | 1686 | |
| Behavioural Message + Video | 1743 |
Breast cancer is the most common cancer in the United Kingdom, with 1 in 8 women affected during their lifetime. Whilst survival rates are high, the 5-year survival rate is 72% higher with the earliest stage breast cancer, compared to the latest disease stage. The National Health Service Breast Screening Programme invites women aged 50 to 70 years old every three years to a mammogram. By enabling earlier detection, it is estimated that the National Health Service Breast Screening Programme saves 1300 lives per year. Despite the potential benefits of breast cancer screening, attendance is falling. Behavioural Science is a field of study concerning understanding the processes underpinning human action. Behavioural theories, such as the Capability Opportunity Motivation-Behaviour model. Recent studies have shown the application of behavioural science to screening may also facilitate uptake of invitations. However, the use of plain text messages limits which behavioural determinants can be feasibly addressed, and what techniques can be used. Video messages can allow for more complex and a broader range of behavioural change techniques to be incorporated, and therefore have greater impact upon attendance. Whilst behavioural science-informed messages have previously been trialed by groups to facilitate breast screening attendance, their effectiveness has been variable. One of the reasons for this, is that text messages are of limited length and formatting capability, thus restricting the number of behavioural change techniques that can be included. Moreover, some behavioural techniques are more complex than others, and plain text can limit the extent to which these can be feasibly incorporated. Video messaging provides a delivery mechanism that may enable more complex, and different combinations to be trialed. There is however, a paucity of data regarding the impact of sending a video-based behavioural science message upon attendance rates at breast cancer screening programmes. This study looks to investigate the impact of a video-message, compared to behavioural science-based text messages and standard reminder messages. The primary object is to determine the impact of behavioural science informed (1) video and (2) text messages compared to usual care, upon uptake of breast cancer screening. Secondary objectives involve how this impact on attendance differs between population subgroups including people from differing demographic groups.
2 peer-reviewed publications reference this trial (live from Europe PMC):
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