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NCT05392842
Corchorus Olitorius Buccal Films for the Treatment of Recurrent Minor Aphthous Ulcerations
Phase 1 trial testing Corchorus Olitorius Buccal fast dissolving Films in Aphthous Ulcer Recurrent in 20 participants. Completed in 1 July 2022.
18 June 2022
Quick facts
| Lead sponsor | Deraya University |
|---|---|
| Phase | Phase 1 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 20 |
| Start date | 10 April 2022 |
| Primary completion | 18 June 2022 |
| Estimated completion | 1 July 2022 |
| Sites | 1 location across Egypt |
Drugs / interventions tested
- Corchorus Olitorius Buccal fast dissolving Films
- plain mucoadhesive fast dissolving film
Conditions studied
- Aphthous Ulcer Recurrent — all drugs for Aphthous Ulcer Recurrent →
Sponsor
Deraya University
Who can join
Adults 18 to 60, any sex, with Aphthous Ulcer Recurrent. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
A methanol extract of Corchorus olitorius edible plant was perpared for extration of glycosideal compounds. the extract was tested for its efficacy as antiinflammatory and analgesic activity invitro and approved by the biomarkers. a fast dissolvinf mucoadhesive film was prepared by a certain amounts of highly safe polymers for a pilote study on human for treament of Aphthous Ulcerations. two groups of study, placebo and intrvention will be recurited and followed for pain, erthymia and size of ulcers for 6 days.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
The Potential of <i>Corchorus olitorius</i> Seeds Buccal Films for Treatment of Recurrent Minor Aphthous Ulcerations in Human Volunteers.
Shady NH, Altemani AH, Altemani FH, Maher SA, et al · · 2022 · cited 9× · PMID 36296628 · DOI 10.3390/molecules27207020
Verify or expand the search:
- PubMed search for NCT05392842
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05392842 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Deraya University
- Last refreshed: 24 October 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05392842.
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