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NCT05387460
Radiomics Based Multimodal Transvaginal Ultrasound Imaging in Endometrial Cancer
trial testing radiomics in Endometrial Cancer in 2,000 participants. Status unknown.
1 December 2022
Quick facts
| Lead sponsor | Tongji Hospital |
|---|---|
| Status | Status unknown |
| Study type | OBSERVATIONAL |
| Enrollment | 2,000 |
| Start date | 1 October 2021 |
| Primary completion | 1 December 2022 |
| Estimated completion | 1 July 2023 |
| Sites | 1 location across China |
Drugs / interventions tested
- radiomics
Conditions studied
- Endometrial Cancer — all drugs for Endometrial Cancer →
- Cervical Stromal Invasion — all drugs for Cervical Stromal Invasion →
- Transvaginal Ultrasound — all drugs for Transvaginal Ultrasound →
Sponsor
Tongji Hospital
Who can join
18 and older, female only, with Endometrial Cancer or Cervical Stromal Invasion. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Retrospectively collect preoperative transvaginal B-mode ultrasound (BMUS), color Doppler flow imaging (CDFI) and three-dimensional ultrasound (3D-US) images and clinical data in patients with non-endometrial cancer diseases and endometrial cancer confirmed by pathology. They were grouped as training set(Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology) and external validation set(Women's Hospital, School of Medicine, Zhejiang University) . Radiomics features were extracted from corresponding transvaginal ultrasound images. Then, the minimum redundancy maximum relevance (mRMR) algorithm and the least absolute shrinkage and selection operator (LASSO) regression were used to select the non- malignant or malignant status-related features and cervical stromal invasion (CSI) status or non-CSI status features and construct the transvaginal ultrasound radiomics score (Rad-score). Multivariate logistic regression was performed using the three radiomics score together with clinical data, and subsequently develop a nomogram to diagnosis endometrial cancer and CSI respectively. The performance of the nomogram was assessed by discrimination, calibration, and clinical usefulness in the training and external validation set.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT05387460
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05387460 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Tongji Hospital
- Last refreshed: 24 May 2022
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