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NCT05383599: CROSP
Characterization of Sperm Population Following Different Selection Procedures
trial in Male Infertility in 50 participants. Status unknown.
16 January 2023
Quick facts
| Lead sponsor | Universitair Ziekenhuis Brussel |
|---|---|
| Status | Status unknown |
| Study type | OBSERVATIONAL |
| Enrollment | 50 |
| Start date | 16 July 2022 |
| Primary completion | 16 January 2023 |
| Estimated completion | 1 August 2023 |
| Sites | 1 location across Belgium |
Conditions studied
- Male Infertility — all drugs for Male Infertility →
Sponsor
Universitair Ziekenhuis Brussel — full company profile →
Who can join
Eligibility, male only, with Male Infertility. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The present study aims to determine which of the sperm selection techniques used in IVF (In Vitro Fertilization) laboratory leads to selection of the best/healthiest sperm population based on their morpho-functional parameters. Different procedures are currently used in our laboratory to select the sperm population that will be used to inseminate the oocytes: Density Gradient Centrifugation (DGC), DGC in combination with Magnetic Activated Sperm Sorting (MACS), and Microfluidic Sperm Sorting (MSS). The sperm cells selected by these techniques will be evaluated for specific morpho-functional features such as, motility, morphological abnormalities, and apoptotic status \[phosphatidylserine translocation (early stages of apoptosis)\] and DNA (Deoxyribonucleic Acid) fragmentation as an indicator of stages of apoptosis.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT05383599
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05383599 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Universitair Ziekenhuis Brussel
- Last refreshed: 6 February 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05383599.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing