Last reviewed · How we verify
NCT05381077: MM-ZTE
Evaluation of Whole Body Examination by MRI Integrating the "Zero Time Eco" Sequence (ZTE, Pseudo-CT) for the Detection of Bone Lesions in Multiple Myeloma: Comparison With Pet / CT and Whole Body Scanner
NA trial testing MRI in Multiple Myeloma in 30 participants. Status unknown.
31 August 2023
Quick facts
| Lead sponsor | Cliniques universitaires Saint-Luc- Université Catholique de Louvain |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | diagnostic |
| Enrollment | 30 |
| Start date | 2 February 2021 |
| Primary completion | 31 August 2023 |
| Estimated completion | 31 August 2023 |
| Sites | 1 location across Belgium |
Drugs / interventions tested
- MRI — full drug profile →
Conditions studied
- Multiple Myeloma — all drugs for Multiple Myeloma →
- Bone Metastases — all drugs for Bone Metastases →
Sponsor
Cliniques universitaires Saint-Luc- Université Catholique de Louvain — full company profile →
Who can join
Adults 18 to 99, any sex, with Multiple Myeloma or Bone Metastases. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
To assess the added value of magnetic resonance imaging (MRI) of the skeleton compared to other validated techniques for the detection of bone lesions in patients with multiple myeloma.
Publications & conference data
3 peer-reviewed publications reference this trial (live from Europe PMC):
-
MRI-based Zero Echo Time and Black Bone Pseudo-CT Compared with Whole-Body CT to Detect Osteolytic Lesions in Multiple Myeloma.
Lecouvet FE, Zan D, Lepot D, Chabot C, et al · · 2024 · cited 7× · PMID 39377681 · DOI 10.1148/radiol.231817 -
Zero echo time MRI with deep learning reconstruction and chemical shift correction for detecting osteolytic myeloma lesions.
Lepot D, Chabot C, Duchêne G, Mandava S, et al · · 2026 · PMID 42247107 · DOI 10.1186/s41747-026-00734-x -
MRI-based pseudo-CT sequences as a radiation-free alternative to CT for obstetric pelvimetry: a proof-of-concept study.
Chabot C, Haegeman M, Chaouch E, Dumitriu D, et al · · 2025 · PMID 40388042 · DOI 10.1186/s41747-025-00585-y
Verify or expand the search:
- PubMed search for NCT05381077
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05381077 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Cliniques universitaires Saint-Luc- Université Catholique de Louvain
- Last refreshed: 19 May 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05381077.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing