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NCT05378451: TOHER
Totally Extraperitoneal Repair of Groin Hernia in Liver Transplanted Patients
trial testing Totally Extraperitoneal Groin Hernia Repair in Liver Transplant Disorder in 10 participants. Completed in 1 January 2024.
1 December 2023
Quick facts
| Lead sponsor | Hospital Clinic of Barcelona |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 10 |
| Start date | 8 May 2022 |
| Primary completion | 1 December 2023 |
| Estimated completion | 1 January 2024 |
| Sites | 1 location across Spain |
Drugs / interventions tested
- Totally Extraperitoneal Groin Hernia Repair
Conditions studied
- Liver Transplant Disorder — all drugs for Liver Transplant Disorder →
- Liver Cirrhosis — all drugs for Liver Cirrhosis →
- Groin Hernia — all drugs for Groin Hernia →
Sponsor
Hospital Clinic of Barcelona
Who can join
18 and older, any sex, with Liver Transplant Disorder or Liver Cirrhosis. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Liver transplant recipients share the risk with cirrhotic patients for the development of inguinal hernias, but their liver failure pathophysiology has reversed following transplantation. Despite immunosuppression alters wound healing and infections, inguinal hernia repair in transplanted patients has shown better outcome compared to cirrhotic patients. Endoscopic inguinal hernia techniques have proved to be superior to open repair, due to lower incidence of postoperative complications and short-term convalescence, but there is no evidence of the use of this approach in liver transplanted patients. This prospective consecutive case series study will be the first study to describe the postoperative results of groin hernia repair in ambulatory surgery regimen in liver transplanted patients using totally extraperitoneal approach. The included patients will be prospectively registered in a standardized database. Rate of completion of surgery by totally extraperitoneal approach without the needing of conversion to anterior open approach or transabdominal preperitoneal approach due technical difficulties will be evaluated. Postoperative complications all along with quality standards criteria of ambulatory surgery will be reported for descriptive purposes.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT05378451
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
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Other Hospital Clinic of Barcelona trials
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05378451 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Hospital Clinic of Barcelona
- Last refreshed: 20 March 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05378451.
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