Last reviewed · How we verify
NCT05377892
The Impact of Dietary Protein on the Metabolome
NA trial testing Dietary protein in Diet, Healthy in 9 participants. Completed in 5 March 2020.
5 March 2020
Quick facts
| Lead sponsor | Stony Brook University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | sequential |
| Masking | none |
| Primary purpose | basic science |
| Enrollment | 9 |
| Start date | 4 November 2019 |
| Primary completion | 5 March 2020 |
| Estimated completion | 5 March 2020 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Dietary protein
Conditions studied
- Diet, Healthy — all drugs for Diet, Healthy →
Sponsor
Stony Brook University
Who can join
Adults 18 to 30, any sex, with Diet, Healthy. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
It is known that tumors have an affinity for taking up amino acids from circulation or nearby tissues to use as a fuel source, to enhance their growth. Work in rodents has shown that when the levels of amino acids are reduced in diet, tumor growth is slowed and tumors are more susceptible to anti-cancer therapies. There are limited evidence-based dietary recommendations for cancer patients, which represents an urgent and unmet need. It is likely that reducing dietary protein will be beneficial, however this has not been tested. In advance of carrying out a study in cancer patients a study in healthy volunteers needs to be conducted to determine whether altering the amount of dietary protein, impacts the levels of amino acids (or other metabolites) in blood or the intestine. By demonstrating that altering dietary protein can alter the metabolome of healthy individuals, it will provide the information needed to reduce protein intake in cancer patients in future studies.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT05377892
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Dietary protein
Trials testing the same drug.
- NCT06721923 — Continuous vs Bolus Protein (Protein Regimen Outcomes) in Critically Ill Children (Kids In Distress) · NA · recruiting
Other recruiting trials for Diet, Healthy
Currently open trials in the same condition.
- NCT06482944 — Whole Food for Families: A Pilot RCT of a Dietary Guidelines-Based Intervention to Prevent Type 2 Diabetes · NA · recruiting
- NCT06814509 — Delivering HOPE (Helping Women Optimize Prenatal Equity) · NA · recruiting
- NCT07027865 — Sip and Snack Better (SSB) Study: Improving Added Sugar in Adolescents · NA · active not recruiting
- NCT06932666 — Why Calories Are Not the Same - a Gut Explanation? · NA · active not recruiting
- NCT07221045 — A Food As Medicine Approach to Address Food Insecurity in Rural North Carolina · NA · recruiting
Other Stony Brook University trials
Trials by the same sponsor.
- NCT07478250 — First Responder Safety Training (FiRST) · NA · not yet recruiting
- NCT07076342 — The Role of mGluR5 in CBT-I · Phase 4 · recruiting
- NCT07009691 — Hydrogen Water Intervention With Heart Rate Variability as an Outcome Biomarker in ME/CFS · NA · recruiting
- NCT07114900 — Randomized Controlled Physical Activity App Intervention for Black Women · Phase 3 · active not recruiting
- NCT05245227 — Double Simultaneous Uterotonic Agents Versus Single Agent Regimen to Prevent Early Postpartum Hemorrhage · Phase 3 · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05377892 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Stony Brook University
- Last refreshed: 17 May 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05377892.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing