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NCT05376384: OC-ESS
Ovarian Cyst's Enucleation Spillage Score
trial testing ultrasound parameters in Ovarian Cysts in 129 participants. Completed in 1 April 2024.
31 March 2024
Quick facts
| Lead sponsor | University of Campania Luigi Vanvitelli |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 129 |
| Start date | 12 May 2022 |
| Primary completion | 31 March 2024 |
| Estimated completion | 1 April 2024 |
| Sites | 1 location across Italy |
Drugs / interventions tested
- ultrasound parameters
- intraoperative parameters
Conditions studied
- Ovarian Cysts — all drugs for Ovarian Cysts →
- Spillage — all drugs for Spillage →
Sponsor
University of Campania Luigi Vanvitelli
Who can join
18 and older, female only, with Ovarian Cysts or Spillage. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Cystic enucleation is one of the most common conservative surgeries in gynecology; it is commonly performed by a minimally invasive approach such as laparoscopy. A high percentage of these surgeries (6-88 % of cases) are complicated by the cystic rupture with intra-abdominal spillage of its contents (spillage). This occurrence affects the surgical and prognostic outcome by lengthening the time of surgery, increasing the risk of postoperative infection or granulomatous peritonitis, of possible second manifestation of the pathology (example: endometriosis), and in the case of neoformation of a carcinomatous nature by leading to an increase in the stage of disease, exposing patients to a prognostic disadvantage and the need for adjuvant treatments also avoidable. In addition, the previous spillage may be associated with the adherent syndrome with repercussions on patients' morbidity and fertility. For these reasons, it is crucial to optimize the selection of patients who are candidates for cystic enucleation. The present study aims to evaluate a series of ultrasound, medical history, and surgical-preoperative parameters to develop a predictive score for the risk of spillage during laparoscopic surgery. Prospective Observational Study. The study aims to enroll 156 patients.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Minimally Invasive Staging of Early-Stage Epithelial Ovarian Cancer versus Open Surgery in Terms of Feasibility and Safety: A Systematic Review and Meta-Analysis.
Ronsini C, Pasanisi F, Molitierno R, Iavarone I, et al · · 2023 · cited 15× · PMID 37298026 · DOI 10.3390/jcm12113831
Verify or expand the search:
- PubMed search for NCT05376384
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of ultrasound parameters
Trials testing the same drug.
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Other recruiting trials for Ovarian Cysts
Currently open trials in the same condition.
- NCT07248553 — Timing of LNG-IUD Insertion and Ovarian Cyst Formation · recruiting
- NCT06913335 — Comparison Between Electrosurgical Energy and Hemostatic Sealants on Hemostasis in Laparoscopic Ovarian Cystectomy · NA · recruiting
- NCT06638593 — MIRRORS-FROZEN - Comparing Open Vs Robotic Surgery in the Management of Women with Complex Pelvic Adnexal Masses ≤ 8cm. · NA · recruiting
- NCT05763511 — Improved Diagnosis of Ovarian Cancer by Use of Circulating Tumor DNA as a Biomarker · recruiting
Other University of Campania Luigi Vanvitelli trials
Trials by the same sponsor.
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- NCT07124676 — Prospective Study Comparing Two Classification Systems for Second-degree Vaginal Tears During Spontaneous Childbirth to · not yet recruiting
- NCT07425912 — Real-World Evaluation of TouchCare Nano in Pediatric Type 1 Diabetes · active not recruiting
- NCT06991816 — The Brain&Senses Study · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05376384 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Campania Luigi Vanvitelli
- Last refreshed: 17 April 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05376384.
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