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NCT05374694: ANFIBIO

Angina, Physiology, Biology (ANgina, FIsiologia BIOlogia)

Status unknown Last updated 19 October 2022
What this trial tests

trial testing Physiological invasive coronary evaluation in Angina Pectoris in 100 participants. Status unknown.

Timeline
8 May 2022
Primary endpoint
31 December 2023
31 December 2023

Quick facts

Lead sponsorHospital Arnau de Vilanova
StatusStatus unknown
Study typeOBSERVATIONAL
Enrollment100
Start date8 May 2022
Primary completion31 December 2023
Estimated completion31 December 2023
Sites1 location across Spain

Drugs / interventions tested

Conditions studied

Sponsor

Hospital Arnau de Vilanova

Who can join

18 and older, any sex, with Angina Pectoris. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Relationship between invasive physiological assessment with FFR and IMR and biological markers as micro-RNA's according to coronary vascular compartiment affected (Group 1: Macrovasculature + / Microvasculature +; Group 2: Macrovasculature + / Microvasculature -; Group 3: Macrovasculature - / Microvasculature +; Group 4: Macrovasculature - / Microvasculature -). Also, biological markers will be related with presence of microvascular spasm or macrovascular spasm (Group 5).

Publications & conference data

4 peer-reviewed publications reference this trial (live from Europe PMC):

  1. MicroRNAs Regulate Function in Atherosclerosis and Clinical Implications.
    Li Z, Zhao Y, Suguro S, Suguro R. · · 2023 · cited 12× · PMID 37675243 · DOI 10.1155/2023/2561509
  2. Study protocol for the epigenetic characterization of angor pectoris according to the affected coronary compartment: Global and comprehensive assessment of the relationship between invasive coronary physiology and microRNAs.
    Matute-Blanco L, Fernández-Rodríguez D, Casanova-Sandoval J, Belmonte T, et al · · 2023 · cited 1× · PMID 37167303 · DOI 10.1371/journal.pone.0283097
  3. Plasma miR-502-5p and coronary artery vasospasm: An exploratory study.
    Matute-Blanco L, Sánchez-Rodríguez M, Casanova-Sandoval J, Garcia-Guimaraes M, et al · · 2026 · PMID 42209331 · DOI 10.1016/j.arteri.2026.500947
  4. Physiological Characterization of Coronary Endotypes: Potential Links with Myocardial Ischemia.
    Matute-Blanco L, Belmonte T, Rivera K, García-Guimaraes M, et al · · 2025 · PMID 41637324 · DOI 10.36660/abc.20250340

Verify or expand the search:

Other recruiting trials for Angina Pectoris

Currently open trials in the same condition.

Other Hospital Arnau de Vilanova trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05374694.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing