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NCT05373381
The KetoGlioma (Ketogenic Glioma) Study
NA trial testing Supplemental High Fat Low Carbohydrate (sHFLC) + KetoPhyt in Glioma. Withdrawn.
18 May 2022
Quick facts
| Lead sponsor | Tufts Medical Center |
|---|---|
| Phase | NA |
| Status | Withdrawn |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | other |
| Start date | 18 May 2022 |
| Primary completion | 18 May 2022 |
| Estimated completion | 18 May 2022 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Supplemental High Fat Low Carbohydrate (sHFLC) + KetoPhyt
Conditions studied
- Glioma — all drugs for Glioma →
Sponsor
Tufts Medical Center
Who can join
18 and older, any sex, with Glioma. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This research is being conducted to see if patients diagnosed with high grade gliomas can adhere to the supplemented High-Fat Low-Carbohydrate (sHFLC) + KetoPhyt diet, and to see how this diet might affect cancer cells in the bloodstream. This diet is experimental and is not routinely prescribed for patients with high-grade gliomas. The results of this study may be used to support larger studies investigating possible anti-tumor affects of the sHFLC + KetoPhyt diet.
Publications & conference data
5 peer-reviewed publications reference this trial (live from Europe PMC):
-
Insight into the Functional Dynamics and Challenges of Exosomes in Pharmaceutical Innovation and Precision Medicine.
Sharma A, Yadav A, Nandy A, Ghatak S. · · 2024 · cited 40× · PMID 38931833 · DOI 10.3390/pharmaceutics16060709 -
The Role of Bacteria in Central Nervous System Tumors: Opportunities and Challenges.
Zhang R, Li X, Zhang S. · · 2024 · cited 6× · PMID 38930435 · DOI 10.3390/microorganisms12061053 -
Diet and Nutrients in Rare Neurological Disorders: Biological, Biochemical, and Pathophysiological Evidence.
Briglia M, Allia F, Avola R, Signorini C, et al · · 2024 · cited 3× · PMID 39339713 · DOI 10.3390/nu16183114 -
The advent of precision nutrigeroscience in cancer: from clinic towards molecular biology.
Gao Z, Liu Y, Cui Y, Han Y, et al · · 2026 · cited 2× · PMID 40850675 · DOI 10.1016/j.jare.2025.08.034 -
Exosomes in glioma: mechanistic insights on biological, therapeutic, and diagnostic perspective.
Tandon R, Kumar S, Handa M, Srivastava N. · · 2025 · PMID 39957239 · DOI 10.1080/20415990.2025.2466410
Verify or expand the search:
- PubMed search for NCT05373381
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05373381 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Tufts Medical Center
- Last refreshed: 2 February 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05373381.
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