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NCT05371704: Multigut
The Effect of Micronutrient Supplementation on Gut Microbiome Composition and Function
NA trial testing Multivitamin Supplementation in Gastrointestinal Microbiome in 24 participants. Status unknown.
1 September 2022
Quick facts
| Lead sponsor | University of Glasgow |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | crossover |
| Masking | none |
| Primary purpose | basic science |
| Enrollment | 24 |
| Start date | 28 September 2021 |
| Primary completion | 1 September 2022 |
| Estimated completion | 1 February 2023 |
| Sites | 1 location across United Kingdom |
Drugs / interventions tested
- Multivitamin Supplementation
- Dietary Replication
Conditions studied
- Gastrointestinal Microbiome — all drugs for Gastrointestinal Microbiome →
Sponsor
University of Glasgow
Who can join
18 and older, any sex, with Gastrointestinal Microbiome. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The main aim of this randomized crossover study is to explore the effect of micronutrient supplementation on gut microbiota composition and function in healthy volunteers. Participants will undertake two 10-day trials with a replicated diet separated by a 15-day washout period. For one of these trials, participants will take a daily over-the-counter multivitamin supplement. Faecal and urine samples will be collected at the start and end of each trial to assess changes in gut microbiota composition, urinary and faecal metabolomics, and targeted bacterial metabolites including short chain fatty acids, sulphide, and lactate.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Micronutrient supplementation influences the composition and diet-originating function of the gut microbiome in healthy adults.
Mckirdy S, Koutsos A, Nichols B, Anderson M, et al · · 2025 · cited 4× · PMID 40645132 · DOI 10.1016/j.clnu.2025.06.020 -
Micronutrient supplementation influences the composition and diet-originating function of the gut microbiome in healthy adults
Mckirdy S, Koutsos A, Nichols B, Anderson M, et al · · 2025
Verify or expand the search:
- PubMed search for NCT05371704
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05371704 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Glasgow
- Last refreshed: 12 May 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05371704.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing