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NCT05371704: Multigut

The Effect of Micronutrient Supplementation on Gut Microbiome Composition and Function

Status unknown NA Last updated 12 May 2022
What this trial tests

NA trial testing Multivitamin Supplementation in Gastrointestinal Microbiome in 24 participants. Status unknown.

Timeline
28 September 2021
Primary endpoint
1 September 2022
1 February 2023

Quick facts

Lead sponsorUniversity of Glasgow
PhaseNA
StatusStatus unknown
Study typeINTERVENTIONAL
Allocationrandomized
Designcrossover
Maskingnone
Primary purposebasic science
Enrollment24
Start date28 September 2021
Primary completion1 September 2022
Estimated completion1 February 2023
Sites1 location across United Kingdom

Drugs / interventions tested

Conditions studied

Sponsor

University of Glasgow

Who can join

18 and older, any sex, with Gastrointestinal Microbiome. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The main aim of this randomized crossover study is to explore the effect of micronutrient supplementation on gut microbiota composition and function in healthy volunteers. Participants will undertake two 10-day trials with a replicated diet separated by a 15-day washout period. For one of these trials, participants will take a daily over-the-counter multivitamin supplement. Faecal and urine samples will be collected at the start and end of each trial to assess changes in gut microbiota composition, urinary and faecal metabolomics, and targeted bacterial metabolites including short chain fatty acids, sulphide, and lactate.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

  1. Micronutrient supplementation influences the composition and diet-originating function of the gut microbiome in healthy adults.
    Mckirdy S, Koutsos A, Nichols B, Anderson M, et al · · 2025 · cited 4× · PMID 40645132 · DOI 10.1016/j.clnu.2025.06.020
  2. Micronutrient supplementation influences the composition and diet-originating function of the gut microbiome in healthy adults
    Mckirdy S, Koutsos A, Nichols B, Anderson M, et al · · 2025

Verify or expand the search:

Other trials of Multivitamin Supplementation

Trials testing the same drug.

Other recruiting trials for Gastrointestinal Microbiome

Currently open trials in the same condition.

Other University of Glasgow trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05371704.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing