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NCT05370092: PNE
Effect of Percutaneous Needle Electrolysis (PNE) on Tendinopathy
NA trial testing Percutaneous needle electrolysis in Posterior Tibial Tendon Dysfunction in 46 participants. Completed in 30 June 2025.
31 January 2025
Quick facts
| Lead sponsor | Universidad Rey Juan Carlos |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 46 |
| Start date | 20 March 2022 |
| Primary completion | 31 January 2025 |
| Estimated completion | 30 June 2025 |
| Sites | 1 location across Spain |
Drugs / interventions tested
- Percutaneous needle electrolysis
- Therapeutic exercise
- Manual therapy
Conditions studied
- Posterior Tibial Tendon Dysfunction — all drugs for Posterior Tibial Tendon Dysfunction →
Sponsor
Universidad Rey Juan Carlos — full company profile →
Who can join
18 and older, any sex, with Posterior Tibial Tendon Dysfunction. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The aim of this study is to test the efficacy of percutaneous electrolysis in posterior tibial tendinopathies. The posterior tibial tendon injury is one of the most frequent pathologies in the lower extremities, and therefore a correct study and evaluation of it is necessary. This study aims to compare the therapeutic effect of percutaneous electrolysis comparing a control group with an experimental group. To evaluate functionality, pain and its ultrasound pattern before and after treatment, in order to assess the efficacy of the treatment.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Ultrasound-guided application of percutaneous electrolysis as an adjunct to exercise and manual therapy for tibialis posterior tendinopathy: A randomized clinical trial.
Rejas-Fernández A, de-la-Llave-Rincón AI, Romero-Morales C, Fernández-de-Las-Peñas C, et al · · 2026 · PMID 41724415 · DOI 10.1016/j.jpain.2026.106236
Verify or expand the search:
- PubMed search for NCT05370092
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Posterior Tibial Tendon Dysfunction
Currently open trials in the same condition.
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Other Universidad Rey Juan Carlos trials
Trials by the same sponsor.
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- NCT07247760 — PATIENT SATISFACTION AND MASKING OF WHITE SPOT LESIONS AFTER HOME WHITENING WITH 10% CARBAMIDE PEROXIDE · NA · enrolling by invitation
- NCT06968676 — Mixed Reality for Upper Limb Rehabilitation in People With Multiple Sclerosis (VIRTUALDOMUS) · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05370092 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Universidad Rey Juan Carlos
- Last refreshed: 25 November 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05370092.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing