NCT05367505 (TIKTIS) is a NA clinical trial of iFuse-3D implant in Pelvic Fracture, sponsored by University of Witten/Herdecke.

Who is sponsoring NCT05367505?

NCT05367505 is sponsored by University of Witten/Herdecke.

What drugs are being tested in NCT05367505?

Interventions in NCT05367505: iFuse-3D implant.

What condition does NCT05367505 study?

NCT05367505 studies Pelvic Fracture, Insufficiency Fractures, Mobility Limitation.

Is NCT05367505 still recruiting?

NCT05367505 is currently recruiting now. Last updated 15 April 2026.

Last reviewed 2026-04-15 · How we verify

NCT05367505: TIKTIS

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Titanium Fusion Implant in Combination With Trans-iliac Screws for Insufficiency Fractures of the Pelvis

Recruiting now NA Last updated 15 April 2026

What this trial tests

NA trial testing iFuse-3D implant in Pelvic Fracture in 60 participants. Currently enrolling.

Timeline

9 January 2023

Primary endpoint
1 December 2026

1 December 2026

Quick facts

Lead sponsor	University of Witten/Herdecke
Phase	NA
Status	Recruiting now
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	treatment
Enrollment	60
Start date	9 January 2023
Primary completion	1 December 2026
Estimated completion	1 December 2026
Sites	3 locations across Germany

Drugs / interventions tested

iFuse-3D implant

Conditions studied

Pelvic Fracture — all drugs for Pelvic Fracture →
Insufficiency Fractures — all drugs for Insufficiency Fractures →
Mobility Limitation — all drugs for Mobility Limitation →

Sponsor

University of Witten/Herdecke

Who can join

60 and older, any sex, with Pelvic Fracture or Insufficiency Fractures. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Many approaches to the surgical treatment of OF-P have been tried, but no one method has stood out as particularly successful. The placement of three implants, including implants that could minimise motion in the sacroiliac joint through early fixation and long-term fusion of the sacroiliac joint, can prevent micromotion in the fracture and thereby improve the clinical outcome of OF-Ps. The iFuse-3D implant was shown to be safe and effective for chronic sacroiliac pain in non-osteoporotic patients. The primary aim is to assess the proportion of patients operated on using iFuse-3D in conjunction with transiliac-transsacral screws who regain pre-fracture mobility by the time of hospital discharge.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Three-dimensional niche-like porous structure locoregionally regulating macrophage immunosenescence rejuvenates aged bone repair.
Zhao DW, Fei X, Zhai H, Zhang Y, et al · · 2026 · PMID 41909511 · DOI 10.1016/j.bioactmat.2026.03.028

Verify or expand the search:

Other recruiting trials for Pelvic Fracture

Currently open trials in the same condition.

NCT06054165 — Impact of a Clinical Pathway for Pelvic Fragility Fractures · NA · recruiting
NCT04937868 — Developing a Decision Instrument to Guide Abdominal-pelvic CT Imaging of Blunt Trauma Patients · recruiting

Other University of Witten/Herdecke trials

Trials by the same sponsor.

NCT06866457 — Audio Hypnosis for Reducing Anxiety in Children and Adolescents Undergoing MRI: A Randomized Controlled Trial · NA · recruiting
NCT06744452 — App-based Stress Management With the mHealth Application "Harmony" · NA · completed
NCT05557890 — System Constellations in Virtual Reality (VR) · NA · active not recruiting
NCT05881551 — Pain Assessment Via Force Measurement Using eEgg After Blockade of the Lumbar Facet Joints · NA · completed
NCT05534282 — Music Therapy With Cancer Affected Children and Their Families · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05367505 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of Witten/Herdecke
Last refreshed: 15 April 2026

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05367505.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing