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NCT05366686: NICE
The Effect of NICE Support Program on Frailty and Quality of Life in Patients With Heart Failure
NA trial testing NICE Support Program in Frailty in 240 participants. Completed in 8 February 2024.
8 February 2024
Quick facts
| Lead sponsor | Ai-Fu Chiou |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | supportive care |
| Enrollment | 240 |
| Start date | 18 January 2022 |
| Primary completion | 8 February 2024 |
| Estimated completion | 8 February 2024 |
| Sites | 1 location across Taiwan |
Drugs / interventions tested
- NICE Support Program
Conditions studied
- Frailty — all drugs for Frailty →
- Quality of Life — all drugs for Quality of Life →
Sponsor
Ai-Fu Chiou
Who can join
20 and older, any sex, with Frailty or Quality of Life. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This RCT study aims to examine effects of a NICE Support Program in heart failure patients. The following hypotheses were tested: patients who received the NICE program will report significant improvement in frailty , social support, anxiety, and depression, quality of life, and nutritional assessment at baseline,4 weeks, 12 weeks and 24 weeks.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Effects of a multimodal support intervention (the NICE-Support programme) on frailty and quality of life in patients with heart failure: a randomized controlled trial.
Wang TC, Hsieh YC, Yang CY, Lee CM, et al · · 2026 · cited 1× · PMID 41482005 · DOI 10.1093/eurjcn/zvaf187
Verify or expand the search:
- PubMed search for NCT05366686
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05366686 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Ai-Fu Chiou
- Last refreshed: 10 July 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05366686.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing