Last reviewed · How we verify
NCT05365334: 3X
Skeletal Muscle and Adipose Tissue Responses After Acute Exercise: Comparing Effects of Three Different Intensities
NA trial testing Low intensity exercise session in Cellular Responses Within Skeletal Muscle in Response to Exercise of Different Intensities in 45 participants. Completed in 23 June 2023.
23 June 2023
Quick facts
| Lead sponsor | University of Michigan |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | basic science |
| Enrollment | 45 |
| Start date | 13 December 2021 |
| Primary completion | 23 June 2023 |
| Estimated completion | 23 June 2023 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Low intensity exercise session
- Moderate intensity exercise session
- High intensity exercise session
Conditions studied
- Cellular Responses Within Skeletal Muscle in Response to Exercise of Different Intensities — all drugs for Cellular Responses Within Skeletal Muscle in Response to Exercise of Different Intensities →
- Relationship Between the Cellular Responses in Skeletal Muscle and the Changes in the Metabolomic Profile — all drugs for Relationship Between the Cellular Responses in Skeletal Muscle and the Changes in the Metabolomic Profile →
- Changes Within Adipose Tissue in Response to Exercise at the Three Different Intensities — all drugs for Changes Within Adipose Tissue in Response to Exercise at the Three Different Intensities →
Sponsor
University of Michigan
Who can join
Adults 18 to 40, any sex, with Cellular Responses Within Skeletal Muscle in Response to Exercise of Different Intensities or Relationship Between the Cellular Responses in Skeletal Muscle and the Changes in the Metabolomic Profile. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The study will assess the exercise-induced changes in chromatin accessibility and gene expression in a cell type-specific manner in skeletal muscle from healthy adults in response to exercise at three different intensities - 1) low-intensity continuous exercise, 2) moderate-intensity continuous exercise, and 3) high-intensity interval exercise.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Molecular responses in abdominal subcutaneous adipose tissue after a session of endurance exercise: effects of exercise intensity.
Ahn C, Zhang T, Rode T, Yang G, et al · · 2025 · cited 3× · PMID 41076654 · DOI 10.1113/jp289339
Verify or expand the search:
- PubMed search for NCT05365334
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05365334 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Michigan
- Last refreshed: 26 July 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05365334.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing