Last reviewed · How we verify
NCT05363462
Topical Antibiotics in Surgical Site
NA trial testing Vancomycin 1000 MG in Surgical Site Infection in 75 participants. Completed in 12 February 2024.
21 December 2023
Quick facts
| Lead sponsor | Universidad Autonoma de Nuevo Leon |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | prevention |
| Enrollment | 75 |
| Start date | 5 January 2022 |
| Primary completion | 21 December 2023 |
| Estimated completion | 12 February 2024 |
| Sites | 1 location across Mexico |
Drugs / interventions tested
- Vancomycin 1000 MG — full drug profile →
Conditions studied
- Surgical Site Infection — all drugs for Surgical Site Infection →
- Complication of Surgical Procedure — all drugs for Complication of Surgical Procedure →
Sponsor
Universidad Autonoma de Nuevo Leon — full company profile →
Who can join
Adults 18 to 65, any sex, with Surgical Site Infection or Complication of Surgical Procedure. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Ankle fractures are one of the most common injuries in traumatology. It is the fourth most common fracture in general population after hip, wrist, and hand fractures. These injuries are the second cause of hospitalization due to fractures. Surgical site infections can be divided according to the Center of Disease Control (CDC) in superficial surgical site infections whose are defined as any infection that happens within the next 30 days after the procedure, they involve only the skin and subcutaneous tissue of the incision, and the patient presents at least one of the following: purulent drainage of the superficial incision, microorganisms isolation from an aseptically obtained culture of body fluid or tissue or the pain existence, tenderness or local inflammation at the superficial incision site despite negative cultures. Also, a diagnosis made by the surgeon or attending medic.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Effect of Topical Vancomycin on Surgical Site Infections in Ankle Fractures: A Randomized, Double-Blind, Controlled Trial.
Acosta-Olivo CA, Hernández-Alejo A, Rangel-Alanís AK, Elizondo-Rodríguez JA, et al · · 2024 · PMID 39092328 · DOI 10.7759/cureus.63694
Verify or expand the search:
- PubMed search for NCT05363462
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Vancomycin 1000 MG
Trials testing the same drug.
- NCT06504992 — Powdered Intrawound Vancomycin in Open Fractures Trial · Phase 4 · not yet recruiting
Other recruiting trials for Surgical Site Infection
Currently open trials in the same condition.
- NCT07501897 — Investigating the Impact of Cold Atmospheric Plasma Treatment on Wound Healing at Cannulation Sites in Patients Followin · NA · recruiting
- NCT07311395 — Local Subcutaneous Gentamicin for Prevention of Surgical Site Infection After Elective Cesarean Section · NA · recruiting
- NCT06649890 — A Novel Surgical Irrigation Solution in Post-Mastectomy Reconstruction: Evaluating Xperience™ · NA · recruiting
- NCT07005635 — The Effects of Different Time Reminder On Surgical Hand Scrubing · NA · active not recruiting
- NCT07049614 — Comparative Study of Postoperative Surgical Site Infections in Diabetic and Non-Diabetic Patients · active not recruiting
Other Universidad Autonoma de Nuevo Leon trials
Trials by the same sponsor.
- NCT07449000 — Losartan for Corneal Fibrosis · NA · recruiting
- NCT07497555 — Anti-Inflammatory Effects of Pecan Nut Oil Supplementation in Adults With Overweight: A Randomized Controlled Parallel-G · NA · recruiting
- NCT06824922 — "Educational Intervention 'Be Yourself': Digital Innovation to Prevent Teenage Pregnancy" · NA · not yet recruiting
- NCT06861478 — PPIs and In-Hospital Morbidity in Acute Variceal Bleeding With Chronic Liver Disease · Phase 2 · recruiting
- NCT06617299 — Cognitive-behavioral Intervention to Increase the Practice of Responsive Feeding and Maintain Healthy Weight in Infants · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05363462 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Universidad Autonoma de Nuevo Leon
- Last refreshed: 14 February 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05363462.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing