NCT05362357 (iSTART) is a NA clinical trial of iSTART Web-app in Substance Use, sponsored by California State University, Northridge.

Who is sponsoring NCT05362357?

NCT05362357 is sponsored by California State University, Northridge.

What drugs are being tested in NCT05362357?

Interventions in NCT05362357: iSTART Web-app.

What condition does NCT05362357 study?

NCT05362357 studies Substance Use, Binge Drinking, Marijuana Use, Alcohol Drinking, Prescription Opioid Misuse, Illicit Drug Use.

Is NCT05362357 still recruiting?

NCT05362357 is currently completed. Last updated 7 February 2024.

Last reviewed 2024-02-07 · How we verify

NCT05362357: iSTART

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

iSTART: A Campus & Community Initiative for Services in Tec-health

Completed NA Last updated 7 February 2024

What this trial tests

NA trial testing iSTART Web-app in Substance Use in 1,100 participants. Completed in 4 December 2023.

Timeline

20 February 2021

Primary endpoint
15 November 2023

4 December 2023

Quick facts

Lead sponsor	California State University, Northridge
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	prevention
Enrollment	1,100
Start date	20 February 2021
Primary completion	15 November 2023
Estimated completion	4 December 2023
Sites	1 location across United States

Drugs / interventions tested

iSTART Web-app

Conditions studied

Substance Use — all drugs for Substance Use →
Binge Drinking — all drugs for Binge Drinking →
Marijuana Use — all drugs for Marijuana Use →
Alcohol Drinking — all drugs for Alcohol Drinking →

Sponsor

California State University, Northridge

Who can join

Adults 18 to 30, any sex, with Substance Use or Binge Drinking. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The iSTART intervention is a 30-day substance prevention web-app whereby students complete five weekly interactive modules using a smart device or computer. Each module is approximately 15 minutes long, and focuses on a select substance: (i) alcohol, (ii) marijuana, (iii) nicotine, (iv) prescription drugs, and (v) illicit drugs. The modules are based on key theoretical constructs, behavior change strategies, and practical module components: attitudes (knowledge), perceived susceptibility (risk perceptions), subjective norms (normative re-education), and self-efficacy (refusal skills). This intervention will be evaluated via a time series design using a sample of 600 students randomly assigned to either the intervention, comparison, or control condition at a public institution in southern California.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Therapeutic Evaluation and Utilization Analysis of Mental Health Prescription Digital Therapeutics Within the Current Regulatory Landscape.
Xia SH, Narayanan MM, Swamy V, Franson K. · · 2025 · cited 3× · PMID 39998017 · DOI 10.3390/pharmacy13010019
Using a multi-module web-app to prevent substance use among students at a Hispanic Serving Institution: development and evaluation design.
Rainisch BKW, Dahlman L, Vigil J, Forster M. · · 2022 · cited 1× · PMID 35705975 · DOI 10.1186/s12889-022-13428-x

Verify or expand the search:

Other recruiting trials for Substance Use

Currently open trials in the same condition.

NCT07075081 — Gii'Igoshimong: Sitting With Your First Family · Phase 2 · recruiting
NCT05743699 — Adaptation and Evaluation of Bright Horizons · NA · recruiting
NCT07509853 — Integrating Sexual Pleasure Into Harm Reduction Services for Men Who Have Sex With Men and Transgender Persons Who Engag · NA · recruiting
NCT06899308 — Health Surveillance at Constructor University Bremen (CUB) and Among HAW-Hamburg Employees · recruiting
NCT07512869 — Host Led Harm Reduction Approach Among Men Who Have Sex With Men Who Engaged in Chemsex in Bangkok, Thailand: A Pre-Impl · recruiting

Other California State University, Northridge trials

Trials by the same sponsor.

NCT06538298 — Title: A Multimodal Exercise Program With Gamification for Parkinson Disease (MEP+G) · EARLY_PHASE1 · recruiting
NCT06553196 — MATAspire: Mental Health Awareness Tailored App for Substance Prevention and Integrated Resilience Education · NA · not yet recruiting
NCT05326555 — Dynamic Vision Testing and Concussion Management Dream Team 65 · unknown
NCT05819489 — A Comparison of Dynamic Vision & Balance Between College Athletes & Controls · unknown
NCT04837066 — Dynamic Vision Testing and Concussion Management · unknown

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05362357 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by California State University, Northridge
Last refreshed: 7 February 2024

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05362357.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing