Last reviewed · How we verify
NCT05361850: CDATE
Comparison of Deep Versus Awake Tracheal Extubation in Adults
NA trial testing Extubation in Airway Complication of Anesthesia in 220 participants. Completed in 26 April 2023.
26 April 2023
Quick facts
| Lead sponsor | United States Navy |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 220 |
| Start date | 28 August 2020 |
| Primary completion | 26 April 2023 |
| Estimated completion | 26 April 2023 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Extubation
Conditions studied
- Airway Complication of Anesthesia — all drugs for Airway Complication of Anesthesia →
- Respiratory Complications of Care — all drugs for Respiratory Complications of Care →
Sponsor
United States Navy
Who can join
Adults 18 to 64, any sex, with Airway Complication of Anesthesia or Respiratory Complications of Care. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Prospective, randomized, single-blinded controlled study to compare the airway and respiratory complications of deep and awake tracheal extubations in adults.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
A comparison of deep versus awake tracheal extubation in adults: a randomized controlled trial.
Lee MA, Schenke PW, Faller MR, DeYoung HR, et al · · 2025 · PMID 40745279 · DOI 10.1186/s12871-025-03224-6
Verify or expand the search:
- PubMed search for NCT05361850
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Extubation
Trials testing the same drug.
- NCT04012073 — Individualized Positive End-expiratory Pressure Guided by End-expiratory Lung Volume in the Acute Respiratory Distress S · Phase 3 · terminated
- NCT04626180 — EFFECT OF PRE EXTUBATION MANUAL HYPERINFLATION TECHNIQUE VS REGULAR EXTUBATION AFTER STERNOTOMY · NA · completed
- NCT02920580 — The NEUROlogically-impaired Extubation Timing Trial · NA · unknown
Other recruiting trials for Airway Complication of Anesthesia
Currently open trials in the same condition.
- NCT06950957 — Video Laryngeal Mask vs. Endotracheal Tube in Septoplasty · recruiting
- NCT06453525 — PrediSuisse: Automatized Assessment of Difficult Airway · recruiting
- NCT06576596 — Apnoeic Oxygenation During Pediatric Tracheal Intubation · NA · recruiting
- NCT05902013 — Video Laryngoscopy Versus Direct Laryngoscopy for Nasotracheal Intubation · NA · recruiting
- NCT04498598 — Structural Modification In Supraglottic Airway Device · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05361850 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by United States Navy
- Last refreshed: 6 May 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05361850.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing