NCT05360498

Symptom Management for Rural-Urban Cancer Survivors and Caregivers

Completed NA Last updated 3 February 2026

What this trial tests

NA trial testing Adaptive Symptom Management and Survivorship Handbook (SMSH) and Telephone Interpersonal Counseling (TIP-C) in Cancer in 555 participants. Completed in 12 January 2026.

Timeline

22 August 2022

Primary endpoint
12 January 2026

12 January 2026

Quick facts

Lead sponsor	University of Arizona
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	sequential
Masking	double
Primary purpose	supportive care
Enrollment	555
Start date	22 August 2022
Primary completion	12 January 2026
Estimated completion	12 January 2026
Sites	1 location across United States

Drugs / interventions tested

• Adaptive Symptom Management and Survivorship Handbook (SMSH) and Telephone Interpersonal Counseling (TIP-C)
• NCI Brochure

Conditions studied

• Cancer — all drugs for Cancer →
• Cancer Survivors — all drugs for Cancer Survivors →
• Informal Caregivers — all drugs for Informal Caregivers →
• Psychological Distress — all drugs for Psychological Distress →

Sponsor

University of Arizona

Who can join

18 and older, any sex, with Cancer or Cancer Survivors. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

As the population of cancer survivors increases substantially, meeting the health care and psychosocial needs of this population has become a national priority. After treatment ends, cancer survivors still experience a range of physical and psychological symptoms that require management. The post-treatment period can present new challenges for many survivors as they encounter communication gaps in the transition from oncology to primary care, leaving unmet needs for information and management of lingering symptoms. The role of informal caregivers remains important during this post-treatment period and psychosocial interventions that meet the needs (e.g., information, symptom management) of both members of the dyad are highly valuable to caregivers and survivors. Many geographic and social determinants of health care use (e.g., distance to specialty care centers, available primary care providers, and public transportation) make access to care and adherence to recommended healthcare guidelines difficult for survivors and caregivers, especially those who reside in rural areas. Rural residents with cancer and their caregivers during the post-treatment period are underrepresented in symptom management research.

To address the unmet needs (e.g., information, symptom management) of cancer survivors and their caregivers after cancer treatment, this team has developed, tested, and investigated two telephone delivered interventions for survivors and their caregivers: Symptom Management and Survivorship Handbook (SMSH) and Telephone Interpersonal Counseling (TIP-C).

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.