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NCT05355558
A Novel Functional Imaging Technique With FLT-PET/MRI For Staging, Response Assessment and Radiation Treatment Planning in Cervix Cancer
NA trial testing [18F]FLT-PET/MRI body scan in Image, Body in 15 participants. Status unknown.
31 December 2022
Quick facts
| Lead sponsor | National Cancer Centre, Singapore |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | diagnostic |
| Enrollment | 15 |
| Start date | 14 May 2019 |
| Primary completion | 31 December 2022 |
| Estimated completion | 31 December 2022 |
| Sites | 1 location across Singapore |
Drugs / interventions tested
- [18F]FLT-PET/MRI body scan
Conditions studied
- Image, Body — all drugs for Image, Body →
- Cervix Cancer — all drugs for Cervix Cancer →
Sponsor
National Cancer Centre, Singapore
Who can join
Adults 21 to 99, any sex, with Image, Body or Cervix Cancer. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This pilot study aims to monitor early tumour response based on \[18F\]FLT-PET/MRI scans and to determine the feasibility of personalised radiotherapy to spare active bone marrow areas identified by \[18F\]FLT-PET/MRI. Bone marrow within the pelvis will be outlined by employing 18FLT PET to identify active BM within bony structures. Subsequently, treatment plans with various conformal radiotherapy techniques will be generated with different optimization approaches toward bone marrow while ensuring adequate tumor coverage. Dosimetric comparison amongst plans will be carried out.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Current Update on PET/MRI in Gynecological Malignancies-A Review of the Literature.
Virarkar M, Vulasala SS, Calimano-Ramirez L, Singh A, et al · · 2023 · cited 5× · PMID 36661732 · DOI 10.3390/curroncol30010083
Verify or expand the search:
- PubMed search for NCT05355558
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05355558 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by National Cancer Centre, Singapore
- Last refreshed: 2 May 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05355558.
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