NCT05351905 is a NA clinical trial of CBD oil ( MPL-001) in Chronic Pain, sponsored by University Health Network, Toronto.

Who is sponsoring NCT05351905?

NCT05351905 is sponsored by University Health Network, Toronto.

What drugs are being tested in NCT05351905?

Interventions in NCT05351905: CBD oil ( MPL-001), CDB+THC oil (MPL-005), Placebo oil.

What condition does NCT05351905 study?

NCT05351905 studies Chronic Pain, Opioid Use, Cannabis.

Is NCT05351905 still recruiting?

NCT05351905 is currently completed. Last updated 14 January 2026.

Last reviewed 2026-01-14 · How we verify

NCT05351905

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Improving Pain Disability With the Use of Oral Cannabinoids

Completed NA Last updated 14 January 2026

What this trial tests

NA trial testing CBD oil ( MPL-001) in Chronic Pain in 51 participants. Completed in 12 January 2026.

Timeline

22 November 2022

Primary endpoint
31 December 2025

12 January 2026

Quick facts

Lead sponsor	University Health Network, Toronto
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	quadruple
Primary purpose	treatment
Enrollment	51
Start date	22 November 2022
Primary completion	31 December 2025
Estimated completion	12 January 2026
Sites	1 location across Canada

Drugs / interventions tested

CBD oil ( MPL-001) — full drug profile →
CDB+THC oil (MPL-005) — full drug profile →
Placebo oil

Conditions studied

Chronic Pain — all drugs for Chronic Pain →
Opioid Use — all drugs for Opioid Use →
Cannabis — all drugs for Cannabis →

Sponsor

University Health Network, Toronto

Who can join

25 and older, any sex, with Chronic Pain or Opioid Use. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The investigators are conducting a pilot (i.e. a small study) in order to find out the effectiveness and safety of medical cannabis in the management of chronic pain. At the end of this 3 month study, investigators will gather information on how easy it is for patients to enroll and complete the entire study. The results of this pilot study will help the study team design a larger randomized controlled trial.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Cannabinoids in Chronic Pain: Clinical Outcomes, Adverse Effects and Legal Challenges.
Sic A, George C, Gonzalez DF, Tseriotis VS, et al · · 2025 · cited 2× · PMID 41002929 · DOI 10.3390/neurolint17090141

Verify or expand the search:

Other recruiting trials for Chronic Pain

Currently open trials in the same condition.

NCT07491549 — The Effect of Pain Education Group Therapy and Its Impact on Chronic Pain, Kinesiophobia, and Physical Activity · NA · recruiting
NCT07425691 — SPACE for Youth With Chronic Pain · recruiting
NCT07103135 — Optimizing Accelerated TMS for Chronic Pain With Thompson Sampling · Phase 1 · recruiting
NCT06219408 — CIH Stepped Care for Co-occurring Chronic Pain and PTSD · NA · recruiting
NCT07270406 — Healthy Behaviors for Insomnia Prevention in People With HIV and Ongoing Pain · NA · recruiting

Other University Health Network, Toronto trials

Trials by the same sponsor.

NCT06831032 — Elective Adaptive Radiation With SBRT for Improved DurabilitY of Response · NA · recruiting
NCT06634056 — Pneumonitis Prevention Protocol Using Pentoxifylline and α-tocopherol In Stage III Non-Small Cell Lung Cancer Patients U · Phase 2 · not yet recruiting
NCT06836726 — Clinical Trial to Test Efficacy of Targeting Hypoxia Combined With ARSI After First-line ARSI Therapy for Castrate Resis · Phase 2 · not yet recruiting
NCT07515651 — Molecular Imaging Informed Radiation Dose Escalation to Sites of Recurrent Disease and De-escalation to Uninvolved Areas · Phase 2 · not yet recruiting
NCT07509450 — Fecal Microbiota Transplantation in Patients Undergoing Chimeric Antigen Receptor T-cell Therapy and Allogeneic Stem Cel · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05351905 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University Health Network, Toronto
Last refreshed: 14 January 2026

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05351905.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing