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NCT05345496
Central and Peripheral Sensitization, Pain Mediators in Thumb Pain Among Physiotherapists
trial in Work-related Illness in 135 participants. Completed in 30 April 2023.
2 March 2023
Quick facts
| Lead sponsor | University of Turin, Italy |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 135 |
| Start date | 2 May 2022 |
| Primary completion | 2 March 2023 |
| Estimated completion | 30 April 2023 |
| Sites | 1 location across Italy |
Conditions studied
- Work-related Illness — all drugs for Work-related Illness →
Sponsor
University of Turin, Italy
Who can join
18 and older, any sex, with Work-related Illness. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The work-related thumb pain is a common problem among physiotherapists which deal with this experience at least once in their life. Several studies analyzed the distribution of mechanical forces, kinematics, and kinesiology of the thumb in this clinical condition. However, there is no data, available in the literature, on how this pain processed is sustained and if plastic changes in the central or peripheral nervous system are involved. The research aims are to investigate the relationship between the thumb pain and pain related central and peripheral nervous sensitization phenomena among physiotherapists (exposed to work) and physiotherapy students (not exposed). The relevance of each of the pain chronification mediators, reported in the literature (anxiety, depression catastrophization, self-efficacy, kinesiophobia) will be also defined. Data on pain intensity, muscle strength, and endurance in the hand will be collected and the relation between peripheral sensitization phenomena in the hand, and central sensitization will be assessed. Also, the relevance of pain mediators and the health perceived status will be assess adopting validated questionnaires and the minimal Generic ICF core set.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT05345496
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05345496 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Turin, Italy
- Last refreshed: 15 February 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05345496.
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