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NCT05344261
Effect of Prophylactic TMR and RPNI on Neuroma and Phantom Limb Pain
NA trial testing Targeted Muscle Re-innervation in Amputation. Withdrawn.
30 December 2024
Quick facts
| Lead sponsor | University of Texas Southwestern Medical Center |
|---|---|
| Phase | NA |
| Status | Withdrawn |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Start date | 1 March 2023 |
| Primary completion | 30 December 2024 |
| Estimated completion | 30 December 2024 |
Drugs / interventions tested
- Targeted Muscle Re-innervation
- Regenerative Peripheral Nerve Interface
- Standard Post-Amputation Surgical Care
Conditions studied
- Amputation — all drugs for Amputation →
- Neuroma Amputation — all drugs for Neuroma Amputation →
- Phantom Limb Pain — all drugs for Phantom Limb Pain →
- Residual Limbs — all drugs for Residual Limbs →
Sponsor
University of Texas Southwestern Medical Center
Who can join
18 and older, any sex, with Amputation or Neuroma Amputation. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The purpose of this study is to analyze the efficacy of novel interventions in post-amputation surgical care (specifically Targeted Muscle Reinnervation and Regenerative Peripheral Nerve Interface) on post-amputation pain and functional outcomes at the time of amputation. These novel interventions have been shown to be successful in treating the downstream effects of amputations (pain, phantom limb pain, neuroma pain, etc.), but has not been studied in a randomized manner at the time of amputation.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT05344261
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
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- Google Scholar
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Other University of Texas Southwestern Medical Center trials
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05344261 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Texas Southwestern Medical Center
- Last refreshed: 5 December 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05344261.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing