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NCT05343052
Hamstring Injury (HAMIR) Index
trial testing Patient Reported Outcomes Surveys in Hamstring Injury in 699 participants. Completed in 5 June 2025.
5 June 2025
Quick facts
| Lead sponsor | University of Wisconsin, Madison |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 699 |
| Start date | 25 April 2022 |
| Primary completion | 5 June 2025 |
| Estimated completion | 5 June 2025 |
| Sites | 5 locations across United States |
Drugs / interventions tested
- Patient Reported Outcomes Surveys
- Clinical Assessments
- Biomechanical and Neuromuscular Assessments
- Conventional MRI
Conditions studied
- Hamstring Injury — all drugs for Hamstring Injury →
Sponsor
University of Wisconsin, Madison
Who can join
Adults 18 to 26, any sex, with Hamstring Injury. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The investigators will combine state-of-the-art quantitative imaging, on-field biomechanics, and computational analytics into the largest-of-its-kind study to assess hamstring strain injury (HSI) risk and recovery in elite collegiate football players. The study will take place over 3 years and enroll up to 560 student athletes from Division I (D1) teams: University of Wisconsin-Madison, Brigham Young University and the University of North Carolina-Chapel Hill.
Publications & conference data
5 peer-reviewed publications reference this trial (live from Europe PMC):
-
The development of a HAMstring InjuRy (HAMIR) index to mitigate injury risk through innovative imaging, biomechanics, and data analytics: protocol for an observational cohort study.
Heiderscheit BC, Blemker SS, Opar D, Stiffler-Joachim MR, et al · · 2022 · cited 7× · PMID 35841053 · DOI 10.1186/s13102-022-00520-3 -
Exploring Sprint Kinematics in American Football Athletes After Anterior Cruciate Ligament Reconstruction.
Ito N, Lin YC, Martin JA, Blemker SS, et al · · 2026 · cited 1× · PMID 41521272 · DOI 10.1111/sms.70200 -
Impact of Prior Hamstring Strain Injury on Muscle Morphology and Sprinting Biomechanics in Collegiate American Football Athletes.
Hulm S, Lin YC, Maniar N, Timmins RG, et al · · 2026 · PMID 42261806 · DOI 10.1111/sms.70317 -
A deep learning algorithm for automatic 3D segmentation and quantification of hamstrings musculotendon injury from MRI.
Riem L, DuCharme O, Coggins A, Kenney A, et al · · 2025 · PMID 41022866 · DOI 10.1038/s41598-025-16926-1 -
The Impact of Localized Muscle Mass on Sprint Mechanics During the Swing and Stance Phases of Division I Collegiate American Football Players.
Metoyer CJ, Lever JR, McGinty M, Landow L, et al · · 2025 · PMID 40570301 · DOI 10.1519/jsc.0000000000005163
Verify or expand the search:
- PubMed search for NCT05343052
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Hamstring Injury
Currently open trials in the same condition.
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- NCT07492732 — Comparison of the Effects of Selected Training Methods and SIS Stimulation on Balance, Motor Tests, and Strength · recruiting
- NCT06526728 — Hyperbaric Oxygen Therapy in HAMstring Injury (HOTHAM) Trial · Phase 3 · recruiting
- NCT05345015 — High Frequency RF Current Effects on Muscle Pain and Function · NA · recruiting
Other University of Wisconsin, Madison trials
Trials by the same sponsor.
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- NCT07475104 — Redesigning Surgical Care for Patients in Wisconsin · NA · enrolling by invitation
- NCT07470723 — The ORIGIN-FH Study · NA · recruiting
- NCT06975657 — Well-being Skills for Reentry · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05343052 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Wisconsin, Madison
- Last refreshed: 11 June 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05343052.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing