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NCT05343052

Hamstring Injury (HAMIR) Index

Completed Last updated 11 June 2025
What this trial tests

trial testing Patient Reported Outcomes Surveys in Hamstring Injury in 699 participants. Completed in 5 June 2025.

Timeline
25 April 2022
Primary endpoint
5 June 2025
5 June 2025

Quick facts

Lead sponsorUniversity of Wisconsin, Madison
StatusCompleted
Study typeOBSERVATIONAL
Enrollment699
Start date25 April 2022
Primary completion5 June 2025
Estimated completion5 June 2025
Sites5 locations across United States

Drugs / interventions tested

Conditions studied

Sponsor

University of Wisconsin, Madison

Who can join

Adults 18 to 26, any sex, with Hamstring Injury. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The investigators will combine state-of-the-art quantitative imaging, on-field biomechanics, and computational analytics into the largest-of-its-kind study to assess hamstring strain injury (HSI) risk and recovery in elite collegiate football players. The study will take place over 3 years and enroll up to 560 student athletes from Division I (D1) teams: University of Wisconsin-Madison, Brigham Young University and the University of North Carolina-Chapel Hill.

Publications & conference data

5 peer-reviewed publications reference this trial (live from Europe PMC):

  1. The development of a HAMstring InjuRy (HAMIR) index to mitigate injury risk through innovative imaging, biomechanics, and data analytics: protocol for an observational cohort study.
    Heiderscheit BC, Blemker SS, Opar D, Stiffler-Joachim MR, et al · · 2022 · cited 7× · PMID 35841053 · DOI 10.1186/s13102-022-00520-3
  2. Exploring Sprint Kinematics in American Football Athletes After Anterior Cruciate Ligament Reconstruction.
    Ito N, Lin YC, Martin JA, Blemker SS, et al · · 2026 · cited 1× · PMID 41521272 · DOI 10.1111/sms.70200
  3. Impact of Prior Hamstring Strain Injury on Muscle Morphology and Sprinting Biomechanics in Collegiate American Football Athletes.
    Hulm S, Lin YC, Maniar N, Timmins RG, et al · · 2026 · PMID 42261806 · DOI 10.1111/sms.70317
  4. A deep learning algorithm for automatic 3D segmentation and quantification of hamstrings musculotendon injury from MRI.
    Riem L, DuCharme O, Coggins A, Kenney A, et al · · 2025 · PMID 41022866 · DOI 10.1038/s41598-025-16926-1
  5. The Impact of Localized Muscle Mass on Sprint Mechanics During the Swing and Stance Phases of Division I Collegiate American Football Players.
    Metoyer CJ, Lever JR, McGinty M, Landow L, et al · · 2025 · PMID 40570301 · DOI 10.1519/jsc.0000000000005163

Verify or expand the search:

Other recruiting trials for Hamstring Injury

Currently open trials in the same condition.

Other University of Wisconsin, Madison trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing