Who is sponsoring NCT05338944?

NCT05338944 is sponsored by University of Manitoba.

What drugs are being tested in NCT05338944?

Interventions in NCT05338944: Dialectical behavioral therapy, Lifestyle.

What condition does NCT05338944 study?

NCT05338944 studies Prevention, Type2Diabetes.

Is NCT05338944 still recruiting?

NCT05338944 is currently recruiting now. Last updated 7 October 2025.

Last reviewed 2025-10-07 · How we verify

NCT05338944

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Dialectal Behaviour Therapy to Enhance Health Behaviour Change for Adolescents Living With Obesity (DIRECTION Trial)

Recruiting now NA Last updated 7 October 2025

What this trial tests

NA trial testing Dialectical behavioral therapy in Prevention in 90 participants. Currently enrolling.

Timeline

14 January 2023

Primary endpoint
1 December 2026

31 January 2027

Quick facts

Lead sponsor	University of Manitoba
Phase	NA
Status	Recruiting now
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	prevention
Enrollment	90
Start date	14 January 2023
Primary completion	1 December 2026
Estimated completion	31 January 2027
Sites	3 locations across Canada

Drugs / interventions tested

Dialectical behavioral therapy
Lifestyle

Conditions studied

Prevention — all drugs for Prevention →
Type2Diabetes — all drugs for Type2Diabetes →

Sponsor

University of Manitoba

Who can join

Adults 14 to 17, any sex, with Prevention or Type2Diabetes. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This research is being conducted to evaluate emotion-focused therapy that incorporates elements of mindfulness, distress tolerance, and relationship support. The investigators want to learn if this therapy, called Dialectical Behavioral Therapy (DBT) will help improve quality of life and weight management in youth at risk for type 2 diabetes. Individuals will be randomly assigned to weekly group based session in one of 3 intervention arms; lifestyle + DBT, lifestyle alone, or a control arm.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Is intensive behavioural change enhanced with dialectical behavioural therapy feasible for weight management in adolescents living with higher body weight? A protocol for a pilot randomised controlled trial in three centres in Canada.
Cameron EE, Morrison KM, Ho J, Roos L, et al · · 2026 · PMID 41688123 · DOI 10.1136/bmjopen-2025-106645

Verify or expand the search:

Other trials of Dialectical behavioral therapy

Trials testing the same drug.

NCT05627492 — Pragmatic Patient-oriented Extension Study of Dialectical Behavior Therapy Booster Sessions for Youth With and/or at Fam · NA · recruiting
NCT04283188 — 12-Month Extension Study of Dialectical Behavior Therapy for Youth With Bipolar Disorder · NA · completed
NCT03661333 — Dissemination and Implementation Field Trial of Dialectical Behavior Therapy for Adolescents With Bipolar Disorder · NA · completed

Other recruiting trials for Prevention

Currently open trials in the same condition.

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NCT07248280 — Adding Aprepitant to a Multimodal Strategy for the Prevention of Postoperative Nausea and Vomiting in High-risk Outpatie · Phase 3 · recruiting
NCT07382583 — Development of a Shared Decision Tool to Facilitate Uptake of the Levonorgestrel-releasing Intrauterine System for the P · recruiting
NCT07498530 — Virtual Assistant for Exercise Adherence in Older ADULTS · NA · recruiting
NCT06682494 — Enhancing Oral Cancer Awareness · NA · recruiting

Other University of Manitoba trials

Trials by the same sponsor.

NCT07528417 — Evaluation of Antibiotic Prophylaxis in Myelodysplastic Syndromes and Acute Myeloid Leukemia (MYELO-CAN:ABX) · Phase 2 · not yet recruiting
NCT07366515 — Feasibility of a Multimodal Virtual Reality Intervention to Reduce Preoperative Anxiety in Cancer Surgery Patients · NA · not yet recruiting
NCT07354386 — Effects of Dried Whole Fruits on Metabolism in Diabetes · NA · enrolling by invitation
NCT07361315 — Development and Online Evaluation of an Online Course for Parasomnias · NA · recruiting
NCT07023744 — CANnabinoids for Drug Resistant Epilepsy (DRE) in Adults and Children · Phase 2 · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05338944 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of Manitoba
Last refreshed: 7 October 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05338944.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing